ListarInvestigación por materia "R loop"
Mostrando ítems 1-5 de 5
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Capítulo de Libro
Detection of DNA-RNA hybrids in vivo
(Humana Press Inc., 2018)DNA-RNA hybrids form naturally during essential cellular functions such as transcription and replication. However, they ...
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Artículo
Gene gating at nuclear pores prevents the formation of R loops
(Taylor and Francis Ltd., 2018)Transcription is an important source of genetic variability. A large amount of transcription-associated genome variation ...
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Artículo
Physical proximity of chromatin to nuclear pores prevents harmful R loop accumulation contributing to maintain genome stability
(National Academy of Sciences, 2017)During transcription, the mRNA may hybridize with DNA, forming an R loop, which can be physiological or pathological, ...
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Artículo
The DNA damage response acts as a safeguardagainst harmful DNA–RNA hybrids ofdifferent origins
(EMBO Press, 2019-07-24)Despite playing physiological roles in specific situations, DNA–RNA hybrids threat genome integrity. To investigate how ...
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Artículo
Yra1-bound RNA–DNA hybrids cause orientation-independent transcription– replication collisions and telomere instability
(Cold Spring Harbor Laboratory Press, 2018)R loops are an important source of genome instability, largely due to their negative impact on replication progression. ...