Browsing by Author "Toledo Aral, Juan José"
Now showing items 1-20 of 33
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Article
A cholinergic neuroskeletal interface promotes bone formation during postnatal growth and exercise.
(CELL PRESS (Elsevier), 2022)The autonomic nervous system is a master regulator of homeostatic processes and stress responses. Sym pathetic noradrenergic ...
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Article
A Single Zinc Finger Motif in the Silencing Factor Rest Represses the Neural-Specific Type II Sodium Channel Promoter.
(PNAS, 1997)The type II voltage-dependent sodium chan- nel is present in neuronal cells, where it mediates the ...
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Article
AQP1 and AQP4 Contribution to Cerebrospinal Fluid Homeostasis
(MDPI, 2019-02-24)Aquaporin 1 (AQP1), expressed in epithelial cells of the choroid plexus, and aquaporin 4 (AQP4) present in ependymal cells ...
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Article
Aquaporin-1 plays important role in proliferation by affecting cell cycle progression
(Wiley, 2016-06-16)Aquaporin-1 (AQP1) has been associated with tumor development. Here, we investigated how AQP1 may affect cell proliferation. ...
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Article
Aquaporin-4 Mediates Permanent Brain Alterations in a Mouse Model of Hypoxia-Aged Hydrocephalus
(MDPI, 2021-09-09)Aquaporin-4 (AQP4) is the principal water channel in the brain being expressed in astrocytes and ependymal cells. AQP4 ...
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Chapter of Book
Carotid Body Transplants as a Therapy for Parkinson’s Disease
(The Royal Society of Chemistry, 2013)Affecting over 1.5 million people across the world, Parkinson's disease is a progressive neurological condition characterized, ...
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PhD Thesis
Characterization of the nigrostriatal pathway in Parkinson's Disease mice models of overexpression of human alpha-synuclein and LRRK2 mutants
(2023-09-05)Parkinson's disease (PD) is a long-term neurodegenerative disease with a complex array of symptoms and signs, involving ...
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Article
Combined effects of aquaporin-4 and hypoxia produce age-related hydrocephalus
(Elsevier, 2018)Aquaporin-4, present in ependymal cells, in glia limiting and abundantly in pericapillary astrocyte foot pro cesses, and ...
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Article
Comparative analysis for the presence of IgG anti-aquaporin-1 in patients with NMO-Spectrum disorders
(MDPI AG, 2016-07-23)Detection of IgG anti-Aquaporin-4 (AQP4) in serum of patients with Neuromyelitis optica syndrome disorders (NMOSD) has ...
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PhD Thesis
Desarrollo in vitro de nuevas terapias dirigidas con nanopartículas para el tratamiento del cáncer de tiroides
(2014)A pesar de que la nanotecnología está siendo aplicada intensamente en la búsqueda de nuevos tratamientos para una amplia ...
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Article
Development of cytosolic hypoxia and hypoxia-inducible factor stabilization are facilitated by aquaporin-1 expression
(Elsevier, 2007)O2 is essential for aerobic life, and the classic view is that it diffuses freely across the plasma membrane. However, ...
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Article
Effects of Rho Kinase Inhibitors on Grafts of Dopaminergic Cell Precursors in a Rat Model of Parkinson's Disease.
(Wiley Online, 2016-04-13)In models of Parkinson’s disease (PD), Rho kinase (ROCK) inhibitors have antiapoptotic and axonstabilizing effects on ...
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PhD Thesis
Enfermedad de parkinson y síntomas urinarios: estudio clínico y en modelos animales
(2008-06-24)Los pacientes con Enfermedad de Parkinson (EP) presentan un mayor porcentaje de síntomas urinarios e incontinencia que la ...
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Article
Full protection from SARS-CoV-2 brain infection and damage in susceptible transgenic mice conferred by MVA-CoV2-S vaccine candidate
(Nature Publishing Group, 2023)Vaccines against SARS-CoV-2 have been shown to be safe and effective but their protective efficacy against infection in ...
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Article
Functional and transcriptional induction of Aquaporin-1 gene by hypoxia; analysis of promoter and role of Hif-1α
(2011)Aquaporin-1 (AQP1) is a water channel that is highly expressed in tissues with rapid O2 transport. It has been reported ...
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PhD Thesis
GDNF y cuerpo carotídeo: implicaciones funcionales y uso en terapia celular
(2007-04-19)El proyecto que se desarrolla en esta Tesis Doctoral se ha centrado en el estudio de los mecanismos celulares y moleculares ...
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Article
Immunization with α-synuclein/Grp94 reshapes peripheral immunity and suppresses microgliosis in a chronic parkinsonism model
(Wiley, 2018)Neuroinflammation mediated by chronically activated microglia, largely caused by abnormal accumulation of misfolded ...
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Article
Is Carotid Body Infection Responsible for Silent Hypoxemia in COVID-19 Patients?
(Oxford University Press (OUP), 2021)