Browsing by Author "López Rivas, Abelardo"
Now showing items 1-8 of 8
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PhD Thesis
Control metabólico de la sensibilidad a TRAIL en células epiteliales de mama : papel de AMPK
(2009)La apoptosis es el mecanismo por el cual las células son eliminadas del organismo tras una serie de procesos bioquímicos ...
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Article
Cytochrome c speeds up caspase cascade activation by blocking 14-3-3ε-dependent Apaf-1 inhibition
(Nature Publishing Group, 2018)Apoptosis is a highly regulated form of programmed cell death, essential to the development and homeostasis of multicellular ...
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Article
Limiting glutamine utilization activates a GCN2/TRAIL-R2/Caspase-8 apoptotic pathway in glutamine-addicted tumor cells
(Springer Nature, 2022)Oncogenic transformation leads to changes in glutamine metabolism that make transformed cells highly dependent on glutamine ...
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Article
Oncogenic p95HER2/611CTF primes human breast epithelial cells for metabolic stress-induced down-regulation of FLIP and activation of TRAIL-R/Caspase-8-dependent apoptosis
(Impact Journals, 2017)Oncogenic transformation triggers reprogramming of cell metabolism, as part of the tumorigenic process. However, metabolic ...
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PhD Thesis
Papel del metabolismo de la glutamina en el control de la sensibilidad a trail de células tumorales de mama.
(2019-01-25)Desde su descubrimiento en 1995, TRAIL ha sido considerado como un ligando de muerte capaz de inducir selectivamente ...
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PhD Thesis
Regulación múltiple de la función del sistema TRAIL en apoptosis
(2017-03-31)El santo grial de la terapia frente al cáncer es encontrar un agente que elimine específica y eficientemente células ...
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PhD Thesis
Role of FLIP and REDD1 in the control of tumor cell fate under endoplasmic reticulum stress
(2022-06-01)During tumor progression, cancer cells face different stress situations as a result of their uncontrolled growth and the ...
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Article
Structural basis for inhibition of the histone chaperone activity of SET/TAF-Iβ by cytochrome c
(National Academy of Sciences, 2015)Chromatin is pivotal for regulation of the DNA damage process insofar as it influences access to DNA and serves as a DNA ...