Browsing by Author "Docobo Pérez, Fernando"
Now showing items 1-13 of 13
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PhD Thesis
Bases moleculares de la resistencia a fosfomicina e implicación de las subpoblaciones con sensibilidad disminuida en su actividad in vitro.
(2018-01-18)El interés global que existe actualmente, en recuperar antibióticos antiguos para el tratamiento de infecciones causadas ...
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Article
Detection of low-level fosfomycin-resistant variants by decreasing glucose-6-phosphate concentration in fosfomycin susceptibility determination
(Multidisciplinary Digital Publishing Institute (MDPI), 2020)Mutations that confer low-level fosfomycin resistance (LLFR) but not clinical resistance in Escherichia coli are increasingly ...
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Article
Disbalancing Envelope Stress Responses as a Strategy for Sensitization of Escherichia coli to Antimicrobial Agents
(Frontiers Media, 2021)Disbalancing envelope stress responses was investigated as a strategy for sensitization of Escherichia coli to antimicrobial ...
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Article
Effect of RecA inactivation and detoxification systems on the evolution of ciprofloxacin resistance in Escherichia coli
(Oxford University Press, 2022)Background Suppression of SOS response and overproduction of reactive oxygen species (ROS) through detoxification system ...
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PhD Thesis
Heterorresistencia a fosfomicina en Escherichia coli: bases moleculares y efecto en su potencial terapéutico
(2022-03-15)En las últimas décadas, el aumento progresivo de la resistencia a los antimicrobianos se ha convertido en un problema ...
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Article
Impaired Virulence and In Vivo Fitness of Colistin-Resistant Acinetobacter baumannii
(Oxford University Press, 2011-01-07)Acinetobacter baumannii (American Type Culture Collection strain 19606) acquires mutations in the pmrB gene during the in ...
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Article
Inoculum Effect on the Efficacies of Amoxicillin-Clavulanate, Piperacillin-Tazobactam, and Imipenem against Extended-Spectrum -Lactamase (ESBL)-Producing and Non-ESBL-Producing Escherichia coli in an Experimental Murine Sepsis Model
(American Society for Microbiology, 2013-04)Escherichia coli is commonly involved in infections with a heavy bacterial burden. Piperacillin-tazobactam and carbapenems ...
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Article
Pharmacodynamics of fosfomycin: Insights into clinical use for antimicrobial resistance
(American Society for Microbiology, 2015-09-01)The aim of this study was to improve the understanding of the pharmacokinetic-pharmacodynamic relationships of fosfomycin ...
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Article
Platelet-activating Factor Receptor Initiates Contact of Acinetobacter baumannii Expressing Phosphorylcholine with Host Cells
(2012-06)Adhesion is an initial and important step in Acinetobacter baumannii causing infections. However, the exact molecular ...
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Presentation
Population pharmacokinetics of colistin: implications for clinical use for Gram-negative pathogens
(2016)The objective of this study was to characterize the pharmacokinetics of colistin methanesulphonate (CMS) and colistin in ...
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Article
Population pharmacokinetics of piperacillin in non-critically ill patients with bacteremia caused by enterobacteriaceae
(MDPI, 2021-03-25)This study analyzes the pharmacokinetic variability of piperacillin in non-critically ill patients with Enterobacteriaceae ...
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Article
Quinolone Resistance Reversion by Targeting the SOS Response
(American Society for Microbiology, 2017)Suppression of the SOS response has been postulated as a therapeutic strategy for potentiating antimicrobial agents. We ...
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PhD Thesis
Tratamientos de la neumonía experimental por Staphylococcus aureus : estudios de eficacia terapéutica de cotrimoxazol, cloxacilina, linezolid y vancomicina frente a cepas S. aureus sensible y resistente a meticilina
(2009)El objetivo general de este proyecto es comparar la actividad de cotrimoxazol, vancomicina, linezolid y cloxacilina ...