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First-in-Human Phase I Study of Iadademstat (ORY-1001): A First-in-Class Lysine-Specific Histone Demethylase 1A Inhibitor, in Relapsed or Refractory Acute Myeloid Leukemia
Salamero, Olga; Montesinos, Pau; Willekens, Christophe; Pérez Simón, José Antonio; Pigneux, Arnaud; Récher, Christian; Somervaille, Tim C.P. (American Society of Clinical Oncology, 2020)PURPOSE Iadademstat is a novel, highly potent, and selective inhibitor of LSD1 (KDM1A), with preclinical in vitro and ...