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Listar por autor "Verdugo Sivianes, Eva María"
Mostrando ítems 1-7 de 7
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Artículo
A new treatment for sarcoma extracted from combination of miRNA deregulation and gene association rules
García Heredia, José Manuel; Perez, Marco; Verdugo Sivianes, Eva María; Martínez Ballesteros, María del Mar; Ortega Campos, Sara M.; Carnero, Amancio (Springer Nature, 2023) -
Artículo
Coordinated downregulation of Spinophilin and the catalytic subunits of PP1, PPP1CA/B/C, contributes to a worse prognosis in lung cancer
Verdugo Sivianes, Eva María; Navas, Lola; Molina Pinelo, Sonia; Quintanal Villalonga, Álvaro Diego; García Heredia, José Manuel; Felipe Abrio, Blanca; Muñoz Galván, Sandra (Impact Journals, 2017)The scaffold protein Spinophilin (Spinophilin, PPP1R9B) is one of the regulatory subunits of phosphatase-1 (PP1), directing ...
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Tesis Doctoral
Estudio de la relevancia de la interacción entre SPN Y PP1 en tumorigénesis
Verdugo Sivianes, Eva María (2019-12-13)El gen SPN es un supresor de tumores importante en la progresión y malignidad tumoral en muchos tipos de tumores, entre ...
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Artículo
New markers for human ovarian cancer that link platinum resistance to the cancer stem cell phenotype and define new therapeutic combinations and diagnostic tools
Muñoz Galván, Sandra; Felipe Abrio, Blanca; García Carrasco, Miguel; Domínguez Piñol, Julia; Suarez Martínez, Elisa; Verdugo Sivianes, Eva María; Espinosa Sánchez, Asunción; Navas Maldonado, Lola Eufemia; Otero Abiol, Daniel; García Heredia, José Manuel; Carnero Moya, Amancio (BMC, 2019)BACKGROUND: Ovarian cancer is the leading cause of gynecologic cancer-related death, due in part to a late diagnosis and ...
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Artículo
Numb-like (NumbL) downregulation increases tumorigenicity, cancer stem cell-like properties and resistance to chemotherapy
García Heredia, José Manuel; Verdugo Sivianes, Eva María; Lucena Cacace, Antonio; Molina Pinelo, Sonia; Carnero Moya, Amancio (Impact Journals, 2016)NumbL, or Numb-like, is a close homologue of Numb, and is part of an evolutionary conserved protein family implicated in ...
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Artículo
Role of the holoenzyme PP1-SPN in the dephosphorylation of the rb family of tumor suppressors during cell cycle
Verdugo Sivianes, Eva María; Carnero Moya, Amancio (MDPI, 2021-05-06)Cell cycle progression is highly regulated by modulating the phosphorylation status of the retinoblastoma protein (pRB) ...
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Artículo
The cargo protein MAP17 (PDZK1IP1) regulates the cancer stem cell pool activating the Notch pathway by abducting NUMB
García Heredia, José Manuel; Lucena Cacace, Antonio; Verdugo Sivianes, Eva María; Pérez, Marco; Carnero Moya, Amancio (American Association for Cancer Research, 2017)Purpose: Cancer stem cells (CSC) are self-renewing tumor cells, with the ability to generate diverse differentiated tumor ...