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Listar por autor "Sydnes, Magne O."
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Artículo
1,4-Dideoxy-1,4-imino-d-arabinitol (DAB) Analogues Possessing a Hydrazide Imide Moiety as Potent and Selective α-Mannosidase Inhibitors
Haarr, Marianne B.; López López, Óscar; Pejov, Ljupcho; Fernández-Bolaños Guzmán, José María; Lindbäck, Emil; Sydnes, Magne O. (American Chemical Society, 2020)The synthesis of two polyhydroxylated pyrrolidines as 1,4-dideoxy-1,4-imino-d-arabinitol (DAB) analogues bearing a hydrazide ...
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Artículo
Development of tacrine clusters as positively cooperative systems for the inhibition of acetylcholinesterase
Evangelista, Tereza Cristina Santos; López López, Óscar; Ferreira, Sabrina Baptista; Fernández-Bolaños Guzmán, José María; Sydnes, Magne O.; Lindbäck, Emil (Taylor & Francis Open Access, 2021)The synthesis of four tetra-tacrine clusters where the tacrine binding units are attached to a central scaffold via linkers ...
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Artículo
Investigation of the Enantioselectivity of Acetylcholinesterase and Butyrylcholinesterase upon Inhibition by Tacrine-iminosugar Heterodimers
Vaaland, I. Caroline; López López, Óscar; Puerta, Adrián; Fernandes, Miguel X.; Padrón, José M.; Fernández-Bolaños Guzmán, José María; Sydnes, Magne O.; Lindback, Emil (Taylor & Francis, 2023)The copper-catalysed azide-alkyne cycloaddition was applied to prepare three enantiomeric pairs of heterodimers containing ...
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Artículo
Tacrine-sugar mimetic conjugates as enhanced cholinesterase inhibitors
Oliveira de Santana, Quelli Larissa; Santos Evangelista, Tereza C.; Imhof, Petra; Ferreira, Sabrina Baptista; Fernández-Bolaños Guzmán, José María; Sydnes, Magne O.; López López, Óscar; Lindback, Emil (Royal Society of Chemistry, 2021-03-14)We have used the Cu(i)-catalyzed azide-alkyne Huisgen cycloaddition reaction to obtain two families of bivalent heterodimers ...