- idUS
- Listar por autor
Listar por autor "Sobrevia Luarte, Luis"
Mostrando ítems 1-20 de 21
-
Artículo
Akt/mTOR Role in Human Foetoplacental Vascular Insulin Resistance in Diseases of Pregnancy
Villalobos Labra, Roberto; Silva, Luis Felipe; Subiabre, Mario; Araos, Joaquín; Salsoso Rodríguez, Rocío; Sobrevia Luarte, Luis (Hindawi Publishing Corporation, 2017)Insulin resistance is characteristic of pregnancies where the mother shows metabolic alterations, such as preeclampsia ...
-
Artículo
Cross Talk between Adipose Tissue and Placenta in Obese and Gestational Diabetes Mellitus Pregnancies via Exosomes
Jayabalan, Nanthini; Nair, Soumyalekshmi; Zuñiga, Felipe A.; Sobrevia Luarte, Luis (Frontiers Media, 2017)Obesity is an important public health issue worldwide, where it is commonly associated with the development of metabolic ...
-
Artículo
Diseases of Pregnancy and Fetal Programming: Cell and Molecular Mechanisms
Sobrevia Luarte, Luis; Myatt, Leslie; Rice, Gregory (Hindawi Publishing Corporation, 2014) -
Artículo
Escherichia coli heat-stable enterotoxin mediates Na+/H+ exchanger 4 inhibition involving cAMP in T84 human intestinal epithelial cells
Beltrán, Ana Rosa; Camarro Lacroix, Luciene R.; Cornejo, Marcelo; Norambuena, Katrina; Toledo, Fernando; Pardos, Fabián; Leiva Mendoza, Andrea; Sobrevia Luarte, Luis; Ramírez, Marco Antonio (Public Library of Science, 2015)The enterotoxigenic Escherichia coli strains lead to diarrhoea in humans due to heat-labile and heat-stable (STa) enterotoxins. ...
-
Artículo
Exosomes derived from monocytes and from endothelial cells mediate monocyte and endothelial cell activation under high d-glucose conditions
Sáez, Tamara; Vos, Paul de; Kuipers, Jeroen; Sobrevia Luarte, Luis; Faas, Marijke M. (Elsevier, 2019)Diabetes mellitus type 2 (DMT2) is characterized by hyperglycemia and associated with low grade inflammation affecting ...
-
Artículo
Fetoplacental endothelial exosomes modulate high d-glucose-induced endothelial dysfunction
Sobrevia Luarte, Luis; Sáez, Tamara; Vos, Paul de; Kuipers, Jeroen; Marijke, M.Faas (Elsevier, 2018)Gestational diabetes mellitus (GDM) is associated with fetoplacental endothelial dysfunction, which may be induced by ...
-
Artículo
Impact of maternal nutrition in viral infections during pregnancy
Mate Barrero, Alfonso; Reyes Goya, Claudia; Santana Garrido, Álvaro; Sobrevia Luarte, Luis; Vázquez Cueto, Carmen María (Elsevier, 2021)Other than being a physiological process, pregnancy is a condition characterized by major adaptations of maternal endocrine ...
-
Artículo
Insulin Reverses D-Glucose–Increased Nitric Oxide and Reactive Oxygen Species Generation in Human Umbilical Vein Endothelial Cells
González, Marcelo; Rojas, Susana; Avila, Pía; Cabrera, Lissette; Villalobos, Roberto; Palma, Carlos; Aguayo, Claudio; Sobrevia Luarte, Luis (Public Library of Science, 2015)Vascular tone is controlled by the L-arginine/nitric oxide (NO) pathway, and NO bioavailability is strongly affected by ...
-
Artículo
Intracellular acidification reduces L-arginine transport via system y + L but not via system y + /CATs and nitric oxide synthase activity in human umbilical vein endothelial cells
Ramírez, Marco Antonio; Morales, Jorge; Cornejo, Marcelo; Blanco, Elias H.; Mancilla-Sierpe, Edgardo; Toledo, Fernando; Beltrán, Ana Rosa; Sobrevia Luarte, Luis (Elsevier, 2018)L-Arginine is taken up via the cationic amino acid transporters (system y + /CATs) and system y + L in human umbilical ...
-
Artículo
Maternal insulin therapy does not restore foetoplacental endothelial dysfunction in gestational diabetes mellitus
Subiabre, Mario; Silva, Luis Q.; Villalobos Labra, Roberto; Toledo, Fernando; Paublo, Mario M.; López, Marcia A.; Salsoso Rodríguez, Rocío; Pardo, Fabián; Leiva, Andrea; Sobrevia Luarte, Luis (Elsevier, 2017)Pregnant women diagnosed with gestational diabetes mellitus subjected to diet (GDMd) that do not reach normal glycaemia ...
-
Artículo
Maternal supraphysiological hypercholesterolemia associates with endothelial dysfunction of the placental microvasculature
Fuenzalida, Bárbara; Sobrevia, Bastián; Cantin, Claudette; Sobrevia Luarte, Luis (Nature Publishing Group, 2018)Maternal physiological or supraphysiological hypercholesterolemia (MPH, MSPH) occurs during pregnancy. MSPH is associated ...
-
Artículo
Modulatory Effect of 2-(4-Hydroxyphenyl)amino-1,4-naphthoquinone on Endothelial Vasodilation in Rat Aorta
Palacios, Javier; Cifuentes, Fredi; Valderrama, Jaime A.; Benites, Julio; Ríos, David; González, Constanza; Sobrevia Luarte, Luis (Hindawi Publishing Corporation, 2016)The vascular endothelium plays an essential role in the control of the blood flow. Pharmacological agents like quinone ...
-
Artículo
Nitric oxide and pH modulation in gynaecological cancer
Sanhueza, Carlos; Araos, Joaquín D.; Naranjo, Luciano; Barros, Eric; Subiabre, Mario; Toledo, Fernando; Gutiérrez, Jaime Agustín; Chiarello, Delia Indira; Pardo, Fabián N.; Leiva, Andrea; Sobrevia Luarte, Luis (Wiley-Blackwell, 2016)Nitric oxide plays several roles in cellular physiology, including control of the vascular tone and defence against pathogen ...
-
Artículo
Nitric Oxide: A Regulator of Cellular Function in Health and Disease
Sobrevia Luarte, Luis; Ooi, Lezanne; Ryan, Scott; Steinert, Joern R. (Hindawi Publishing Corporation, 2016) -
Artículo
Oxidative and Inflammatory Imbalance in Placenta and Kidney of sFlt1-Induced Early-Onset Preeclampsia Rat Model
Santana Garrido, Álvaro; Reyes Goya, Claudia; Espinosa Martín, Pablo; Sobrevia Luarte, Luis; Beltrán Romero, Luis Matías; Vázquez Cueto, Carmen María; Mate Barrero, Alfonso (Multidisciplinary Digital Publishing Institute (MDPI), 2022)Preeclampsia (PE) is a pregnancy-specific disorder characterized by the new onset of hypertension plus proteinuria and/or ...
-
Artículo
Oxidative stress: Normal pregnancy versus preeclampsia
Chiarello, Delia Indira; Abad, Cilia; Rojas, Deliana; Toledo, Fernando; Vázquez Cueto, Carmen María; Mate Barrero, Alfonso; Sobrevia Luarte, Luis; Marín, Reinaldo (Elsevier, 2020)The role of oxidative stress in the physiopathology of human pregnancy is of particular interest. Pregnancy is well-known ...
-
Artículo
Pathophysiological and molecular considerations of viral and bacterial infections during maternal-fetal and –neonatal interactions of SARS-CoV-2, Zika, and Mycoplasma infectious diseases
Ferreira, Gonzalo; Blassina, Fernanda; Rey, Marianela; Anesetti, Gabriel; Sapiro, Rosana; Chavarría, Luisina; Sobrevia Luarte, Luis (Elsevier, 2021)During pregnancy, a series of physiological changes are determined at the molecular, cellular and macroscopic level that ...
-
Artículo
Reduced L-carnitine transport in aortic endothelial cells from spontaneously hypertensive rats
Salsoso Rodríguez, Rocío; Guzmán Gutiérrez, Enrique; Arroyo Zúñiga, Pablo; Salomón Gallo, Carlos; Zambrano Sevilla, Sonia; Ruiz Armenta, María Victoria; Blanca Lobato, Antonio Jesús; Pardo, Fabián; Leiva Mendoza, Andrea; Mate Barrero, Alfonso; Sobrevia Luarte, Luis; Vázquez Cueto, Carmen María (Public Library of Science, 2014)Impaired L-carnitine uptake correlates with higher blood pressure in adult men, and L-carnitine restores endothelial ...
-
Tesis Doctoral
La regulación del transporte de L-arginina vía HCAT-1 por insulina involucra activación diferencial de los subtipos A y B de receptores de insulina y receptores de adenosina en células endoteliales de vena umbilical humana de diabetes gestacional
Guzmán Gutiérrez, Enrique Alberto (2014-01-29)Diabetes gestacional (DG) aumenta el transporte de L-arginina en la macrocirculación de la placenta. Insulina activa ...
-
Artículo
Role for Tetrahydrobiopterin in the Fetoplacental Endothelial Dysfunction in Maternal Supraphysiological Hypercholesterolemia
Leiva Mendoza, Andrea; Fuenzalida, Bárbara; Westermeier, Francisco; Toledo, Fernando; Salomón Gallo, Carlos; Gutiérrez, Jaime; Sanhueza, Carlos; Sobrevia Luarte, Luis (Hindawi Publishing Corporation, 2015)Maternal physiological hypercholesterolemia occurs during pregnancy, ensuring normal fetal development. In some cases, the ...