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Listar por autor "Ortiz Padilla, Miriam"
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Artículo
Contribution of hypermutation to fosfomycin heteroresistance in Escherichia coli
Portillo Calderón, Inés María; Ortiz Padilla, Miriam; Rodríguez Martínez, José Manuel; De Gregorio Iaria, Belén; Blázquez, Jesús; Rodríguez-Baño, Jesús; Pascual Hernández, Álvaro; Docobo Pérez, Fernando (Oxford University Press, 2020)Objectives: To explore the effect of combining defects in DNA repair systems with the presence of fosfomycin-resistant ...
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Artículo
Effect of Glycerol on Fosfomycin Activity against Escherichia coli
Ortiz Padilla, Miriam; Portillo Calderón, Inés María; Velázquez Escudero, Ana; Rodríguez-Baño, Jesús; Pascual Hernández, Álvaro; Rodríguez Martínez, José Manuel; Docobo Pérez, Fernando (Multidisciplinary Digital Publishing Institute (MDPI), 2022)Fosfomycin is an antimicrobial that inhibits the biosynthesis of peptidoglycan by entering the bacteria through two channels ...
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Artículo
Evaluation of temocillin efficacy against KPC-2-producing Klebsiella pneumoniae isolates in a hollow-fibre infection model
Rodríguez Ochoa, José Luis; Pérez Palacios, Patricia; Merino Bohórquez, Vicente; Ortiz Padilla, Miriam; Velázquez Escudero, Ana; Rodríguez-Baño, Jesús; Rodríguez Martínez, José Manuel; Pascual Hernández, Álvaro; Docobo Pérez, Fernando (Oxford University Press, 2024-02-09)Background: Temocillin is an old antimicrobial that is resistant to hydrolysis by ESBLs but has variable activity against ...
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Tesis Doctoral
Optimisation of the therapeutic potential of fosfomycin against Enterobacteriaceae: characterisation of genetic and physiological factors related to resistance and antimicrobial activity
Ortiz Padilla, Miriam (2023-05-30)Since the discovery of the first antimicrobials, bacteria with resistance mechanisms against them have been detected. The ...
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Artículo
Role of low-level quinolone resistance in generating tolerance in Escherichia coli under therapeutic concentrations of ciprofloxacin
Ortiz Padilla, Miriam; Díaz Díaz, S.; Machuca, J.; Tejada-Gonzalez, A.; Recacha, E.; Docobo Pérez, Fernando; Pascual Hernández, Álvaro; Rodríguez Martínez, José Manuel (Oxford University Press, 2020)Background: Tolerance (including persistence) and resistance result in increased survival under antibiotic pressure. Objectives: ...