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Listar por autor "Monaco, Serena"
Mostrando ítems 1-7 de 7
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Artículo
Exploring Multi-Subsite Binding Pockets in Proteins: DEEP-STD NMR Fingerprinting and Molecular Dynamics Unveil a Cryptic Subsite at the GM1 Binding Pocket of Cholera Toxin B
Monaco, Serena; Walpole, Samuel; Doukani, Hassan; Nepravishta, Ridvan; Martínez Bailén, Macarena; Carmona Asenjo, Ana Teresa; Ramos Soriano, Francisco Javier; Robina Ramírez, Inmaculada; Angulo Álvarez, Jesús (Wiley, 2020)Ligand-based NMRtechniquesto studyprotein–ligandinteractionsare potenttoolsin drugdesign.Satura-tiontransfer difference ...
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Fucosidases from the human gut symbiont Ruminococcus gnavus
Wu, Haiyang; Rebello, Osmond; Owen, C. David; Walpole, Samuel; Bennati Granier, Chloe; Ndeh, Didier; Monaco, Serena; Angulo Álvarez, Jesús (Springer, 2021)The availability and repartition of fucosylated glycans within the gastrointestinal tract contributes to the adaptation ...
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Inter-Ligand STD NMR: An Efficient 1D NMR Approach to Probe Relative Orientation of Ligands in a Multi-Subsite Protein Binding Pocket
Monaco, Serena; Ramírez Cárdenas, Jonathan; Carmona Asenjo, Ana Teresa; Robina Ramírez, Inmaculada; Angulo Álvarez, Jesús (Multidisciplinary Digital Publishing Institute (MDPI), 2022)In recent years, Saturation Transfer Difference NMR (STD NMR) has been proven to be a powerful and versatile ligand-based ...
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Multifrequency STD NMR Unveils the Interactions of Antibiotics With Burkholderia multivorans Biofilm Exopolysaccharide
Nepravishta, Ridvan; Monaco, Serena; Distefano, Marco; Rizzo, Roberto; Cescutti, Paola; Angulo Álvarez, Jesús (Frontiers Media S.A., 2021)Biofilms confine bacterial cells within self-produced matrices, offering advantages such as protection from antibiotics ...
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Spatially Resolved STD-NMR Applied to the Study of Solute Transport in Biphasic Systems: Application to Protein-Ligand Interactions
Nepravishta, Ridvan; Monaco, Serena; Muñoz García, Juan Carlos; Khimyak, Yaroslav Z.; Angulo Álvarez, Jesús (SAGE Publications, 2019)Fluid biphasic systems are one of the most interesting dynamic systems in chemistry and biochemistry. In nuclear magnetic ...
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Uncovering a novel molecular mechanism for scavenging sialic acids in bacteria
Bell, Andrew; Severi, Emmanuele; Lee, Micah; Monaco, Serena; Latousakis, Dimitrios; Angulo, Jesús; Thomas, Gavin H.; Naismith, James H.; Juge, Nathalie (American Society for Biochemistry and Molecular Biology, 2020)The human gut symbiont Ruminococcus gnavus scavenges host-derived N-acetylneuraminic acid (Neu5Ac) from mucins by converting ...
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Unravelling the specificity and mechanism of sialic acid recognition by the gut symbiont Ruminococcus gnavus
Owen, C. David; Tailford, Louise E.; Monaco, Serena; Šuligoj, Tanja; Vaux, Laura; Lallement, Romane; Angulo Álvarez, Jesús; Juge, Nathalie (Nature Research, 2017)Ruminococcus gnavus is a human gut symbiont wherein the ability to degrade mucins is mediated by an intramolecular ...