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Listar por autor "McArthur, Grant A."
Mostrando ítems 1-3 de 3
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Artículo
5-year outcomes with cobimetinib plus vemurafenib in BRAFV600 mutation⇓positive advanced melanoma: extended follow-up of the coBRIM study
Ascierto, Paolo Antonio; Dreno, Brigitte; Larkin, James; Ribas, Antoni; Cruz Merino, Luis de la; McArthur, Grant A. (American Association for Cancer Research, 2021)Purpose: The randomized phase III coBRIM study (NCT01689519) demonstrated improved progression-free survival (PFS) and ...
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Artículo
Clinical features of serous retinopathy observed with cobimetinib in patients with BRAF‑mutated melanoma treated in the randomized coBRIM study
Cruz Merino, Luis de la; Di Guardo, Lorenza; Grob, Jean Jacques; Venosa, Alfredo; Larkin, James; McArthur, Grant A.; Dreno, Brigitte (Biomed Central LTD, 2017)Background: Serous chorioretinopathy has been associated with MEK inhibitors, including cobimetinib. We describe the ...
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Artículo
Terminal osteoblast differentiation, mediated by runx2 and p27 KIP1, is disrupted in osteosarcoma
Gutiérrez Pozo, Gabriel; Thomas, David M.; Johnson, Sandra A.; Sims, Natalie A.; Trivett, Melanie K.; Slavin, John L.; Rubin, Brian P.; Waring, Paul; McArthur, Grant A.; Walkley, Carl R.; Holloway, Andrew J.; Diyagama, Dileepa; Grim, Jonathon E.; Clurman, Bruce E.; Bowtell, David D. L.; Lee, Jong-Seo; Piscopo, Denise M.; Carty, Shannon A.; Hinds, Philip W. (Rockefeller University Press, 2004)The molecular basis for the inverse relationship between differentiation and tumorigenesis is unknown. The function of ...