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Listar por autor "Hontecillas Prieto, Lourdes"
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Ewing Sarcoma Meets Epigenetics, Immunology and Nanomedicine: Moving Forward into Novel Therapeutic Strategies
Sánchez Molina, Sara; Figuerola Bou, Elisabet; Sánchez Margalet, Víctor; Cruz Merino, Luis de la; Mora, Jaume; Álava Casado, Enrique de; García-Domínguez, Daniel J.; Hontecillas Prieto, Lourdes (MDPI, 2022-11-07)Ewing Sarcoma (EWS) is an aggressive bone and soft tissue tumor that mainly affects children, adolescents, and young adults. ...
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HMGA2 overexpression predicts relapse susceptibility of blastemal Wilms tumor patients
Hontecillas Prieto, Lourdes; García-Domínguez, Daniel J.; García Mejías, Rosa; Ramírez Villar, Gema; Sáez, Carmen; Álava Casado, Enrique de (Impact Journals, 2017)Wilms tumor (WT) is an embryonal malignant neoplasm of the kidney that accounts for 6–7% of all childhood cancers. WT ...
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Multidrug resistance transporter profile reveals MDR3 as a marker for stratification of blastemal Wilms tumour patients
Hontecillas Prieto, Lourdes; García-Domínguez, Daniel J.; Pascual Vaca, Diego; García Mejías, Rosa; Marcilla, David; Ramírez Villar, Gema; Álava Casado, Enrique de (Impact Journals, 2017)Wilms tumour (WT) is the most common renal tumour in children. Most WT patients respond to chemotherapy, but subsets of ...
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Obesity and Risk for Lymphoma: Possible Role of Leptin
Jiménez Cortegana, Carlos; Hontecillas Prieto, Lourdes; García-Domínguez, Daniel J.; Zapata, Fernando; Palazón Carrión, Natalia; Sánchez León, María Luisa; Tami, Malika; Pérez Pérez, Antonio; Sánchez Jiménez, Flora; Vilariño García, Teresa; Cruz Merino, Luis de la; Sánchez Margalet, Víctor (MDPI, 2022-12-08)Obesity, which is considered a pandemic due to its high prevalence, is a risk factor for many types of cancers, including ...
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Selective histone methyltransferase G9a inhibition reduces metastatic development of Ewing sarcoma through the epigenetic regulation of NEU1
García-Domínguez, Daniel J.; Hajji, Nabil; López Alemany, Roser; Sánchez Molina, Sara; Figuerola Bou, Elisabet; Morón Civanto, Francisco Jesús; Álava Casado, Enrique de; Hontecillas Prieto, Lourdes (Nature Publishing Group, 2022)Ewing sarcoma (EWS) is an aggressive bone and soft tissue tumor with high susceptibility to metastasize. The underlying ...
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Selective inhibition of HDAC6 regulates expression of the oncogenic driver EWSR1-FLI1 through the EWSR1 promoter in Ewing sarcoma
García-Domínguez, Daniel J.; Hajji, Nabil; Sánchez Molina, Sara; Figuerola Bou, Elisabet; Martínez de Pablos, Rocío; Espinosa Oliva, Ana María; Flores Campos, Rocío; Robles Frías, María José; Álava Casado, Enrique de; Hontecillas Prieto, Lourdes (Springer Nature, 2021)Ewing sarcoma (EWS) is an aggressive bone and soft tissue tumor of children and young adults in which the principal driver ...
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Synergistic Enhancement of Cancer Therapy Using HDAC Inhibitors: Opportunity for Clinical Trials
Hontecillas Prieto, Lourdes; Flores Campos, Rocío; Silver, Andrew; Álava Casado, Enrique de; Hajji, Nabil; García-Domínguez, Daniel J. (Frontiers Media S.A., 2020)Chemotherapy is one of the most established and effective treatments for almost all types of cancer. However, the elevated ...
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The bitter side of epigenetics: variability and resistance to chemotherapy
Hajji, Nabil; García-Domínguez, Daniel J.; Hontecillas Prieto, Lourdes; O'Neill, Kevin; Álava Casado, Enrique de; Syed, Nelofer (Future Medicine, 2021)One of the major obstacles to the development of effective new cancer treatments and the main factor for the increasing ...
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Tumor Immune Microenvironment in Lymphoma: Focus on Epigenetics
García-Domínguez, Daniel J.; Hontecillas Prieto, Lourdes; Palazón Carrión, Natalia; Jiménez Cortegana, Carlos; Sánchez Margalet, Víctor; Cruz Merino, Luis de la (MDPI, 2022)Lymphoma is a neoplasm arising from B or T lymphocytes or natural killer cells characterized by clonal lymphoproliferation. ...