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Listar por autor "Grünewald, Thomas G. P."
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Artículo
Integrative clinical transcriptome analysis reveals TMPRSS2-ERG dependency of prognostic biomarkers in prostate adenocarcinoma
Gerke, Julia S.; Orth, Martin F.; Tolkach, Yuri; Romero Pérez, Laura; Wehweck, Fabienne S.; Stein, Stefanie; Grünewald, Thomas G. P. (Wiley, 2020)In prostate adenocarcinoma (PCa), distinction between indolent and aggressive disease is challenging. Around 50% of PCa ...
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Artículo
Therapeutic targeting of the PLK1-PRC1-axis triggers cell death in genomically silent childhood cancer
Li, Jing; Ohmura, Shunya; Marchetto, Aruna; Orth, Martin F.; Imle, Roland; Dallmayer, Marlene; Romero Pérez, Laura; Grünewald, Thomas G. P. (Nature Research, 2021-09-16)Chromosomal instability (CIN) is a hallmark of cancer1. Yet, many childhood cancers, such as Ewing sarcoma (EwS), feature ...
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Artículo
Translational evidence for RRM2 as a prognostic biomarker and therapeutic target in Ewing sarcoma
Ohmura, Shunya; Marchetto, Aruna; Orth, Martin F.; Li, Jing; Jabar, Susanne; Ranft, Andreas; Romero Pérez, Laura; Grünewald, Thomas G. P. (BMC, 2021-07-27)Ewing sarcoma (EwS) is an aggressive bone- or soft tissue-associated malignancy, characterised by the fusion oncoprotein ...