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Listar por autor "García Rodríguez, Néstor"                

Mostrando ítems 1-5 de 5

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      BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote continuous DNA synthesis 

      Salas Lloret, Daniel; García Rodríguez, Néstor; Soto Hidalgo, Emily; González Vinceiro, Lourdes; Espejo Serrano, Carmen; Giebel, Lisanne; Huertas Sánchez, Pablo; González Prieto, Román (Nature Research, 2024-05-20)
      Deficiencies in the BRCA1 tumor suppressor gene are the main cause of hereditary breast and ovarian cancer. BRCA1 is ...
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      Impaired manganese metabolism causes mitotic misregulation 

      García Rodríguez, Néstor; Díaz de la Loza, María del Carmen; Andreson, Bethany; Monje Casas, Fernando; Rothstein, Rodney; Wellinger, Ralf Erik (American Society for Biochemistry and Molecular Biology, 2012)
      Manganese is an essential trace element, whose intracellular levels need to be carefully regulated. Mn2+ acts as a cofactor ...
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      Manganese is a physiologically relevant TORC1 activator in yeast and mammals 

      Nicastro, Raffaele; Gaillard, Hélène; Zarzuela, Laura; Peli-Gulli, Marie-Pierre; Fernández García, Elisabet; Tomé, Mercedes; García Rodríguez, Néstor; Durán, Raúl V.; De Virgilio, Claudio; Wellinger, Ralf Erik (eLife Sciences Publications, 2022)
      The essential biometal manganese (Mn) serves as a cofactor for several enzymes that are crucial for the prevention of human ...
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      Manganese Redistribution by Calcium-stimulated Vesicle Trafficking Bypasses the Need for P-type ATPase Function 

      García Rodríguez, Néstor; Manzano López, Javier; Muñoz Bravo, Miguel; Fernández García, Elisabet; Muñiz Guinea, Manuel; Wellinger, Ralf Erik (American Society for Biochemistry and Molecular Biology, 2015)
      Regulation of intracellular ion homeostasis is essential for eukaryotic cell physiology. An example is provided by loss ...
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      Non-recombinogenic roles for Rad52 in translesion synthesis during DNA damage tolerance 

      Cano Linares, María Isabel; Yáñez Vilches, Aurora; García Rodríguez, Néstor; Barrientos Moreno, Marta; González Prieto, Román; San Segundo, Pedro; Ulrich, Helle D.; Prado, Félix (Wiley-Blackwell, 2021)
      DNA damage tolerance relies on homologous recombination (HR) and translesion synthesis (TLS) mechanisms to fill in the ...