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Artículo
Contribution of hypermutation to fosfomycin heteroresistance in Escherichia coli
Portillo Calderón, Inés María; Ortiz Padilla, Miriam; Rodríguez Martínez, José Manuel; De Gregorio Iaria, Belén; Blázquez, Jesús; Rodríguez-Baño, Jesús; Pascual Hernández, Álvaro; Docobo Pérez, Fernando (Oxford University Press, 2020)Objectives: To explore the effect of combining defects in DNA repair systems with the presence of fosfomycin-resistant ...
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Artículo
Interplay Among Different Fosfomycin Resistance Mechanisms in Klebsiella Pneumoniae
Ortiz Padilla, M.; Portillo Calderón, I.; De Gregorio Iaria, Belén; Blázquez, J.; Rodríguez-Baño, Jesús; Pascual Hernández, Álvaro; Rodríguez Martínez, José Manuel; Docobo Pérez, Fernando (American Society for Microbiology, 2021)The objectives of this study were to characterize the role of the uhpT, glpT, and fosA genes in fosfomycin resistance in ...
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Artículo
RecA inactivation as a strategy to reverse the heteroresistance phenomenon in clinical isolates of Escherichia coli
Díaz Díaz, S.; Yerbes, Pilar; Recacha, E.; De Gregorio Iaria, Belén; Pulido, Marina R.; Romero-Muñoz, María; Docobo Pérez, Fernando; Pascual Hernández, Álvaro; Rodríguez Martínez, José Manuel (Elsevier, 2023-02)RecA inhibition could be an important strategy to combat antimicrobial resistance because of its key role in the SOS ...
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Artículo
Synergistic effect of SOS response and GATC methylome suppression on antibiotic stress survival in Escherichia coli
Díaz Díaz, S.; Recacha, E.; Pulido, Marina R.; Romero Muñoz, María; De Gregorio Iaria, Belén; Docobo Pérez, Fernando; Pascual Hernández, Álvaro; Rodríguez Martínez, José Manuel (https://journals.asm.org/doi/epdf/10.1128/aac.01392-22, 2023-03)The suppression of the SOS response has been shown to enhance the in vitro activity of quinolones. Furthermore, Dam-dependent ...