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Listar por autor "Clemente, Francesca"
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Artículo
Piperidine Azasugars Bearing Lipophilic Chains: Stereoselective Synthesis and Biological Activity as Inhibitors of Glucocerebrosidase (GCase)
Clemente, Francesca; Matassini, Camilla; Giachetti, Sara; Goti, Andrea; Morrone, Amelia; Martínez Bailén, Macarena; Orta, Sara; Merino, Pedro; Cardona, Francesca (American Chemical Society, 2021)We report a straightforward synthetic strategy for the preparation of trihydroxypiperidine azasugars decorated with ...
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Artículo
Synthesis of “All-Cis” Trihydroxypiperidines from a Carbohydrate-Derived Ketone: Hints for the Design of New β-Gal and GCase Inhibitors
Davighi, Maria Giulia; Clemente, Francesca; Matassini, Camilla; Martínez Bailén, Macarena; Cardona, Francesca; Goti, Andrea (MDPI, 2020)Pharmacological chaperones (PCs) are small compounds able to rescue the activity of mutated lysosomal enzymes when used ...