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Listar por autor "Ceña, Valentín"
Mostrando ítems 1-5 de 5
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Artículo
A β-Cyclodextrin-Based Nanoparticle with Very High Transfection Efficiency Unveils siRNA-Activated TLR3 Responses in Human Prostate Cancer Cells
de la Torre, Cristina; Játiva, Pablo; Posadas, Inmaculada; Manzanares, Darío; Jiménez Blanco, José Luis; Ortiz Mellet, Carmen; García Fernández, José Manuel; Ceña, Valentín (Multidisciplinary Digital Publishing Institute (MDPI), 2022)Synthetic double-stranded small interfering RNAs (siRNAs) mimic interference RNAs (RNAi) and can bind target mRNAs with a ...
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Artículo
Cyclodextrin-Based Nanostructure Efficiently Delivers siRNA to Glioblastoma Cells Preferentially via Macropinocytosis
Manzanares, Darío; Pérez Carrión, Mª Dolores; Jiménez Blanco, José Luis; Ortiz Mellet, Carmen; García Fernández, José Manuel; Ceña, Valentín (MDPI, 2020)Small interfering ribonucleic acid (siRNA) has the potential to revolutionize therapeutics since it can knockdown very ...
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Artículo
Docetaxel-Loaded Nanoparticles Assembled from β-Cyclodextrin/Calixarene Giant Surfactants: Physicochemical Properties and Cytotoxic Effect in Prostate Cancer and Glioblastoma Cells
Gallego-Yerga, Laura; Posadas, Inmaculada; Torre, Cristina de la; Ruiz-Almansa, Jesús; Sansone, Francesco; Ortiz Mellet, Carmen; Casnati, Alessandro; García Fernández, José Manuel; Ceña, Valentín (Frontiers Media, 2017)Giant amphiphiles encompassing a hydrophilic β-cyclodextrin (βCD) component and a hydrophobic calix[4]arene (CA4) module ...
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Artículo
Molecular Determinants for Cyclo-oligosaccharide-based Nanoparticle-mediated Effective siRNA Transfection
Manzanares, Darío; Araya Durán, Ingrid; Gallego Yerga, Laura; Játiva, Pablo; Márquez Miranda, Valeria; Canan, Jonathan; Jiménez Blanco, José Luis; Ortiz Mellet, Carmen; González Nilo, Fernando Danilo; García Fernández, José Manuel; Ceña, Valentín (Future Medicine Ltd., 2017)Aim: To study the structural requirements that a cyclooligosaccharide-based nanoparticle must fulfill to be an efficient ...
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Artículo
Nanoparticle-delivered HIV peptides to dendritic cells a promising approach to generate a therapeutic vaccine
Martín Moreno, Alba; Jiménez Blanco, José Luis; Mosher, Jamie; Swanson, Douglas R.; García Fernández, José Manuel; Sharma, Ajit; Ceña, Valentín; Muñoz Fernández, María Angeles (Multidisciplinary Digital Publishing Institute (MDPI), 2020)Finding a functional cure for HIV-1 infection will markedly decrease the social and economic burden of this disease. In ...