- idUS
- Listar por autor
Listar por autor "Bayona Feliu, Aleix"
Mostrando ítems 1-9 de 9
-
Artículo
Centriolar Subdistal Appendages Promote Double-strand Break Repair Through Homologous Recombination
Rodriguez Real, Guillermo; Domínguez Calvo, Andrés; Prados Carvajal, Rosario; Bayona Feliu, Aleix; Gomes Pereira, Sonia; Romero Balestra, Fernando; Huertas Sánchez, Pablo (1469-3178, 2023)The centrosome is a cytoplasmic organelle with roles in microtu-bule organization that has also been proposed to act as a ...
-
Artículo
Human THO–Sin3A interaction reveals new mechanisms to prevent R-loops that cause genome instability
Salas Armenteros, Irene; Pérez Calero, Carmen; Bayona Feliu, Aleix; Tumini, Emanuela; Luna Varo, Rosa María; Aguilera López, Andrés (Wiley-Blackwell, 2017)R-loops, formed by co-transcriptional DNA–RNA hybrids and a displaced DNA single strand (ssDNA), fulfill certain positive ...
-
Artículo
Linker histone H1 prevents R-loop accumulation and genome instability in heterochromatin
Bayona Feliu, Aleix; Casas Lamesa, Anna; Reina, Óscar; Bernués, J.; Azorín, Fernando (Nature Publishing Group, 2017)Linker histone H1 is an important structural component of chromatin that stabilizes the nucleosome and compacts the ...
-
Artículo
TDP-43 mutations link Amyotrophic Lateral Sclerosis with R-loop homeostasis and R loop-mediated DNA damage
Giannini, Marta; Bayona Feliu, Aleix; Sproviero, Daisy; Barroso, Sonia I.; Cereda, Cristina; Aguilera López, Andrés (Public Library of Science, 2020)TDP-43 is a DNA and RNA binding protein involved in RNA processing and with structural resemblance to heterogeneous ...
-
Artículo
The chromatin network helps prevent cancer-associated mutagenesis at transcription-replication conflicts
Bayona Feliu, Aleix; Herrera Moyano, Emilia; Badra Fajardo, Nibal; Galván Femenía, Iván; Soler Oliva, María Eugenia; Aguilera López, Andrés (Nature Research, 2023)Genome instability is a feature of cancer cells, transcription being an important source of DNA damage. This is in large ...
-
Artículo
The role of chromatin at transcription-replication conflicts as a genome safeguard
Bayona Feliu, Aleix; Aguilera López, Andrés (Portland Press, 2021)DNA replication ensures the correct copying of the genome and the faithful transfer of the genetic information to the ...
-
Artículo
The SWI/SNF chromatin remodeling complex helps resolve R-loop-mediated transcription–replication conflicts
Bayona Feliu, Aleix; Barroso Ceballos, Sonia Inés; Muñoz Sánchez, Sergio; Aguilera López, Andrés (Springer Nature, 2021)ATP-dependent chromatin remodelers are commonly mutated in human cancer. Mammalian SWI/SNF complexes comprise three conserved ...
-
Artículo
The SWI/SNF complex, transcription-replication conflicts and cancer: a connection with high therapeutic potential
Bayona Feliu, Aleix; Aguilera López, Andrés (Taylor & Francis, 2021)Genome instability is a hallmark of cancer. ATP-dependent chromatin remodelers are frequently altered in cancer. We have ...
-
Artículo
UAP56/DDX39B is a major cotranscriptional RNA–DNA helicase that unwinds harmful R loops genome-wide
Pérez Calero, Carmen; Bayona Feliu, Aleix; Xue, Xiaoyu; Barroso Ceballos, Sonia Inés; Muñoz Sánchez, Sergio; González Basallote, Víctor M.; Sung, Patrick; Aguilera López, Andrés (Cold Spring Harbor Laboratory Press, 2020)Nonscheduled R loops represent a major source of DNA damage and replication stress. Cells have different ways to prevent ...