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Artículo
Detection and Quantitative Analysis of Two Independent Binding Modes of a Small Ligand Responsible for DC-SIGN Clustering
Guzzi, Cinzia; Alfarano, Pietro; Sutkeviciute, Ieva; Sattin, Sara; Ribeiro Viana, Renato; Fieschi, Franck; Bernardi, Anna; Weiser, Joerg; Rojo, Javier; Angulo, Jesús; Nieto, Pedro M. (Royal Society of Chemistry, 2015)DC-SIGN (dendritic cell-specific ICAM-3 grabbing non-integrin) is a C-type lectin receptor (CLR) present, mainly in dendritic ...
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Artículo
Speeding-up the Determination of Protein-Ligand Affinities by STD NMR: The Reduced Data Set STD NMR Approach (rd-STD NMR)
Rocha, Gabriel; Ramírez Cárdenas, Jonathan; Padilla Pérez, María del Carmen; Walpole, Samuel; Nepravishta, Ridvan; García Moreno, M. Isabel; Sánchez Fernández, Elena Matilde; Ortiz Mellet, Carmen; Angulo, Jesús; Muñoz García, Juan Carlos (American Chemical Society, 2024-01-02)STD NMR spectroscopy is a powerful ligand-observed NMR tool for screening and characterizing the interactions of small ...
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Artículo
Synthesis of amine-functionalized heparin oligosaccharides for the investigation of carbohydrate-protein interactions in microtiter plates
Maza Pérez, Susana; Macchione, Giuseppe; Ojeda, Rafael; López Prados, Javier; Angulo, Jesús; Paz, José L. de; Nieto, Pedro M. (Royal Society of Chemistry (Great Britain), 2012)The synthesis of well-defined oligosaccharides is crucial for the establishment of structure-activity relationships for ...
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Artículo
Uncovering a novel molecular mechanism for scavenging sialic acids in bacteria
Bell, Andrew; Severi, Emmanuele; Lee, Micah; Monaco, Serena; Latousakis, Dimitrios; Angulo, Jesús; Thomas, Gavin H.; Naismith, James H.; Juge, Nathalie (American Society for Biochemistry and Molecular Biology, 2020)The human gut symbiont Ruminococcus gnavus scavenges host-derived N-acetylneuraminic acid (Neu5Ac) from mucins by converting ...