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Listar por autor "Tabares, Lucía"
Mostrando ítems 21-40 de 47
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Artículo
Functional regeneration of the murine neuromuscular synapse relies on long‑lasting morphological adaptations
Bermedo García, Francisca; Zelada, Diego; Martínez, Esperanza; Tabares, Lucía; Henríquez, Juan Pablo (BMC, 2022)Background: In a broad variety of species, muscle contraction is controlled at the neuromuscular junction (NMJ), the ...
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Artículo
HERC1 Ubiquitin Ligase Is Required for Normal Axonal Myelination in the Peripheral Nervous System
Bachiller, Sara; Roca Ceballos, María Angustias; García Domínguez, Irene; Pérez Villegas, Eva María; Martos Carmona, David; Pérez Castro, Miguel Ángel; Real Navarrete, Luis Miguel; Rosa, José Luis; Tabares, Lucía; Venero Recio, José Luis; Armengol, José Ángel; Carrión, Ángel Manuel; Ruiz Laza, Rocío (Springer, 2018-03-30)A missense mutation in HERC1 provokes loss of cerebellar Purkinje cells, tremor, and unstable gait in tambaleante (tbl) ...
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Tesis Doctoral
Identificación de componentes moleculares sinápticos que contribuyen a la vulnerabilidad de los terminales nerviosos motores en un modelo múrido de atrofia muscular espinal
Tejero Navarro, Rocío (2016-11-28)La Atrofia Muscular Espinal (AME), la causa genética más frecuente de mortalidad infantil, es una enfermedad neurodegenerativa ...
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Tesis Doctoral
Incremento de la concentración de calcio intracelular inducida por dopamina en celulas pineales de rata
Rey Gaitán, Carlos Elkin (1999-05-04) -
Artículo
Monitoring synaptic function at the neuromuscular junction of a mouse expressing synaptopHluorin
Tabares, Lucía; Ruiz Laza, Rocío; Linares Clemente, Pedro; Gaffield, Michael A.; Álvarez de Toledo Naranjo, Guillermo; Fernández-Chacón, Rafael; Betz, William J. (2007)We monitored presynaptic exocytosis and vesicle recycling at neuromuscular junctions of transgenic mice expressing ...
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Tesis Doctoral
Monitorización de la función sináptica normal y patológica en modelos animales
Ruiz Laza, Rocío (2009-04-17)El objetivo principal de esta Tesis Doctoral ha sido el estudio de la transmisión sináptica en la unión neuromuscular. El ...
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Artículo
Morphological and functional remodelling of the neuromuscular junction by skeletal muscle PGC-1 alpha
Arnold, Anne Sophie; Gill, Jonathan; Christe, Martine; Ruiz Laza, Rocío; McGuirk, Shawn; St-Pierre, Julie; Tabares, Lucía; Handschin, Christoph (NATURE PUBLISHING GROUP, 2014-04-04)The neuromuscular junction (NMJ) exhibits high morphological and functional plasticity. In the mature muscle, the relative ...
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Artículo
Multiple Functions of the Vesicular Proton Pump in Nerve Terminals
Tabares, Lucía; Betz, Bill (Cell Press, 2010-12-22)Synaptic vesicles are acidified by a proton pump (vATPase), which allows vesicular uptake of neurotransmitters. After ...
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Artículo
Neuroprotective effect of adult hematopoietic stem cells in a mouse model of motoneuron degeneration
Cabanes, Carmen; Bonilla, Sonia; Tabares, Lucía; Martínez, Salvador (2007)Degenerative spinal motor diseases, like amyotrophic lateral sclerosis, are produced by progressive degeneration ...
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Artículo
Neuroprotective effect of adult hematopoietic stem cells in a mouse model of motoneuron degeneration
Cabanes, Carmen; Bonilla, Sonia; Tabares, Lucía; Martínez, Salvador (2007)Degenerative spinal motor diseases, like amyotrophic lateral sclerosis, are produced by progressive degeneration of ...
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Artículo
Notch Signaling Pathway Is Activated in Motoneurons of Spinal Muscular Atrophy
Lladó, Jerònia; Caraballo Miralles, Víctor; Tabares, Lucía; Torres Benito, Laura; Cardona Rossinyol, Andrea; Olmos, Gabriel; Garcera, Ana; Solar, Rosa María (2013) -
Tesis Doctoral
Papel de la proteína de supervivencia de la motoneurona (SMN) en la maduración sináptica
Franco Espín, Julio (2021-07-30)La atrofia muscular espinal (AME), la causa genética más frecuente de mortalidad infantil, es una enfermedad neurodegenerativa ...
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Artículo
Preferred Sites of Exocytosis and Endocytosis Colocalize during High- But Not Lower-Frequency Stimulation in Mouse Motor Nerve Terminals
Gaffield, Michael A.; Tabares, Lucía; Betz, William J. (SOC NEUROSCIENCE, 2009)The spatial relationship of exocytosis and endocytosis in motor nerve terminals has been explored, with varied results, ...
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Artículo
Presynaptic Mitochondria Communicate With Release Sites for Spatio-Temporal Regulation of Exocytosis at the Motor Nerve Terminal
López Manzaneda, Mario; Fuentes Moliz, Andrea; Tabares, Lucía (Frontiers Research Foundation, 2022)Presynaptic Ca2+ regulation is critical for accurate neurotransmitter release, vesicle reloading of release sites, and ...
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Artículo
Properties of Calcium and Potassium Currents of Clonal Adrenocortical Cells
López Barneo, José; Tabares, Lucía; Ureña López, Juan (1989)The ionic currents of clonal Y-1 adrenocortical cells were studied using the whole-cell variant of the patch-clamp technique. ...
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Artículo
R-Roscovitine Improves Motoneuron Function in Mouse Models for Spinal Muscular Atrophy
Tejero, Rocío; Balk, Stefanie; Franco-Espin, Julio; Ojeda Orellana, Jorge; Hennlein, Luisa; Drexl, Hans; Tabares, Lucía; Jablonka, Sibylle (Elsevier, 2020-02-21)Neurotransmission defects and motoneuron degeneration are hallmarks of spinal muscular atrophy, a monogenetic disease ...
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Artículo
SMN Is Physiologically Downregulated at Wild-Type Motor Nerve Terminals but Aggregates Together with Neurofilaments in SMA Mouse Models
Franco Espín, Julio; Gatius, Alaó; Armengol, José Ángel; Arumugam, Saravanan; Moradi, Mehri; Sendtner, Michael; Calderó, Jordi; Tabares, Lucía (MDPI, 2022-10-20)muscular atrophy (SMA). SMN forms the core of a protein complex localized at the cytoplasm and nuclear gems and that ...
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Artículo
SMN Requirement for Synaptic Vesicle, Active Zone and Microtubule Postnatal Organization in Motor Nerve Terminals
Torres Benito, Laura; Feodora Neher, Margret; Cano, Raquel; Tabares, Lucía (2011-10-12)Low levels of the Survival Motor Neuron (SMN) protein produce Spinal Muscular Atrophy (SMA), a severe monogenetic disease ...
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Artículo
Smn-Deficiency Increases the Intrinsic Excitability of Motoneurons
Arumugam, Saravanan; Garcera, Ana; Soler, Rosa M.; Tabares, Lucía (2017-09-05)During development, motoneurons experience significant changes in their size and in the number and strength of connections ...
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Artículo
Synaptic defects in spinal muscular atrophy animal models
Torres-Benito, Laura; Ruiz Laza, Rocío; Tabares, Lucía (Wiley, 2011)Proximal spinal muscular atrophy, the most frequent genetic cause of childhood lethality, is caused by homozygous loss ...