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Listar por autor "García Heredia, José Manuel"
Mostrando ítems 21-25 de 25
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Artículo
Sarcoma stratification by combined pH2AX and MAP17 (PDZK1IP1) levels for a better outcome on doxorubicin plus olaparib treatment
Pérez, Marco; García Heredia, José Manuel; Felipe Abrio, Blanca; Muñoz Galván, Sandra; Martín Broto, Javier; Carnero Moya, Amancio (Springer Nature, 2020)Sarcomas constitute a rare heterogeneous group of tumors, including a wide variety of histological subtypes. Despite ...
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Specific nitration of tyrosines 46 and 48 makes cytochrome c assemble a non-functional apoptosome
García Heredia, José Manuel; Díaz Moreno, Irene; Díaz Quintana, Antonio Jesús; Orzáez, Mar; Navarro Carruesco, José Antonio; Hervás Morón, Manuel; Rosa Acosta, Miguel Ángel de la (Elsevier, 2012)Under nitroxidative stress, a minor fraction of cytochrome c can be modified by tyrosine nitration. Here we analyze the ...
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The cargo protein MAP17 (PDZK1IP1) regulates the cancer stem cell pool activating the Notch pathway by abducting NUMB
García Heredia, José Manuel; Lucena Cacace, Antonio; Verdugo Sivianes, Eva María; Pérez, Marco; Carnero Moya, Amancio (American Association for Cancer Research, 2017)Purpose: Cancer stem cells (CSC) are self-renewing tumor cells, with the ability to generate diverse differentiated tumor ...
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The cargo protein MAP17 (PDZK1IP1) regulates the immune microenvironment
García Heredia, José Manuel; Carnero Moya, Amancio (Impact Journals, 2017)Inflammation is a complex defensive response activated after various harmful stimuli allowing the clearance of damaged ...
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The Multitasker Protein: A Look at the Multiple Capabilities of NUMB
Ortega Campos, Sara M.; García Heredia, José Manuel (Multidisciplinary Digital Publishing Institute (MDPI), 2023)NUMB, a plasma membrane-associated protein originally described in Drosophila, is involved in determining cell function ...