Author profile: Burguillos García, Miguel Ángel
Data
| Name | Burguillos García, Miguel Ángel |
| Department | Bioquímica y Biología Molecular |
| Knowledge area | Bioquímica y Biología Molecular |
| Professional category | Investigador Contratado (Ramón y Cajal) |
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Statistics
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Items
19
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2862
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3324
| Publications |
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Article
 Cell Death Related Proteins Beyond Apoptosis in the CNS
(Frontiers Media S.A., 2022-01-01)
Cell death related (CDR) proteins are a diverse group of proteins whose original function was ascribed to apoptotic cell ... |
Final Degree Project
COVID-19: manifestaciones neurológicas asociadas y efectos sobre la neurodegeneración
(2021-01-01)
El SARS-CoV2 (coronavirus de tipo 2 causante del síndrome respiratorio agudo severo) responsable de la enfermedad COVID-19, ... |
Article
TET2, an ambiguous player in inflammation
(2020-01-01)
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Article
Microglia: Agents of the CNS Pro-Inflammatory Response
(Multidisciplinary Digital Publishing Institute (MDPI), 2020-01-01)
The pro-inflammatory immune response driven by microglia is a key contributor to the pathogenesis of several neurodegenerative ... |
Article
Reformulating Pro-Oxidant Microglia in Neurodegeneration
(MDPI, 2019-01-01)
In neurodegenerative diseases, microglia-mediated neuroinflammation and oxidative stress are central events. Recent ... |
Article
TET2 Regulates the Neuroinflammatory Response in Microglia
(Elsevier, 2019-01-01)
Epigenomic mechanisms regulate distinct aspects of the inflammatory response in immune cells. Despite the central role for ... |
Article
Brainiac Caspases: Beyond the Wall of Apoptosis
(Frontiers Media, 2019-01-01)
For the last two decades, caspases, a family of cysteine-aspartic proteases, have evolved from being considered solely as ... |
Article
Magnetofection as a new tool to study microglia biology
(Medknow Publications, 2019-01-01)
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PhD Thesis
Papel de la galectina-3 en la respuesta inmune y en la pérdida neuronal asociada a un modelo murino de daño cerebral traumático.
(2018-07-13)
La lesión cerebral traumática (TBI) es actualmente una causa importante de muerte y discapacidad en la sociedad occidental, ... |
Article
Effective Knockdown of Gene Expression in Primary Microglia With siRNA and Magnetic Nanoparticles Without Cell Death or Inflammation
(Frontiers Media, 2018-01-01)
Microglia, the resident immune cells of the brain, have multiple functions in physiological and pathological conditions, ... |
Article
Galectin-3 released in response to traumatic brain injury acts as an alarmin orchestrating brain immune response and promoting neurodegeneration
(Nature, 2017-01-01)
Traumatic brain injury (TBI) is currently a major cause of morbidity and poor quality of life in Western society, with an ... |
Article
Spatio-temporal activation of caspase-8 in myeloid cells upon ischemic stroke
(BioMed Central, 2016-01-01)
Ischemic stroke (caused by thrombosis, embolism or vasoconstriction) lead to the recruitment and activation of immune cells ... |
PhD Thesis
A dual tool. The role of the ripoptosome in phagocytic cell activation and differentiation
(2015-10-19)
El término ripoptosoma hace referencia a la plataforma molecular que contiene, entre otras, dos proteínas implicadas en ... |
Article
Microglia-secreted galectin-3 acts as a toll-like receptor 4 ligand and contributes to microglial activation
(2015-01-01)
Inflammatory response induced by microglia plays a critical role in the demise of neuronal populations in neuroinflammatory ... |
Article
Deletion of caspase-8 in mouse myeloid cells blocks microglia pro-inflammatory activation and confers protection in MPTP neurodegeneration model
(Impact Journals, LLC, 2015-01-01)
Increasing evidence involves sustained pro-inflammatory microglia activation in the pathogenesis of different neurodegenerative ... |
Article
Neuromelanin activates proinflammatory microglia through a caspase-8-dependent mechanism
(BioMed Central, 2015-01-01)
Background We have uncovered a caspase-dependent (caspase-8/caspase-3/7) signaling governing microglia activation and ... |
Article
Regulation of caspase-3 processing by cIAP2 controls the switch between pro-inflammatory activation and cell death in microglia
(Nature Publishing Group, 2014-01-01)
The activation of microglia, resident immune cells of the central nervous system, and inflammation-mediated neurotoxicity ... |
Article
The role of Galectin-3 in α-synuclein-induced microglial activation
(BioMed Central, 2014-01-01)
Background: Parkinson ’ s disease (PD) is the most prevalent neurodegenerative motor disorder. The neuropathology ... |
| PhD Thesis |