Data

NameBurguillos García, Miguel Ángel
DepartmentBioquímica y Biología Molecular
Knowledge areaBioquímica y Biología Molecular
Professional categoryInvestigador Contratado (Ramón y Cajal)
E-mailRequest
           

  Statistics

  • Items

    19

  • Visits

    2862

  • Downloads

    3324

  Publications

 

Article
Icon

Cell Death Related Proteins Beyond Apoptosis in the CNS

Bahatyrevich-Kharitonik, Bazhena; Medina Guzmán, Rafael; Flores Cortés, Alicia; García Cruzado, Marta; Kavanagh, Edel T.; Burguillos García, Miguel Ángel (Frontiers Media S.A., 2022-01-01)
Cell death related (CDR) proteins are a diverse group of proteins whose original function was ascribed to apoptotic cell ...
Final Degree Project
Icon

COVID-19: manifestaciones neurológicas asociadas y efectos sobre la neurodegeneración

Burguillos García, Miguel Ángel; Morillo García, Claudia (2021-01-01)
El SARS-CoV2 (coronavirus de tipo 2 causante del síndrome respiratorio agudo severo) responsable de la enfermedad COVID-19, ...
Article
Icon

TET2, an ambiguous player in inflammation

Espinosa Oliva, Ana María; Burguillos García, Miguel Ángel (2020-01-01)
Article
Icon

Microglia: Agents of the CNS Pro-Inflammatory Response

Rodríguez Gómez, José Antonio; Kavanagh, Edel T.; Engskog-Vlachos, Pinelopi; Engskog, Mikael; Herrera Carmona, Antonio José; Espinosa Oliva, Ana María; Joseph, Bertrand; Hajji, Nabil; Venero Recio, José Luis; Burguillos García, Miguel Ángel (Multidisciplinary Digital Publishing Institute (MDPI), 2020-01-01)
The pro-inflammatory immune response driven by microglia is a key contributor to the pathogenesis of several neurodegenerative ...
Article
Icon

Reformulating Pro-Oxidant Microglia in Neurodegeneration

García Revilla, Juan; Alonso Bellido, Isabel María; Burguillos García, Miguel Ángel; Herrera Carmona, Antonio José; Espinosa Oliva, Ana María; Ruiz Laza, Rocío; Cruz Hernández, Luis; García Domínguez, Irene; Roca Ceballos, María Angustias; Santiago Pavón, Martiniano; Rodríguez Gómez, José Antonio; Sarmiento Soto, Manuel; Martínez de Pablos, Rocío; Venero Recio, José Luis (MDPI, 2019-01-01)
In neurodegenerative diseases, microglia-mediated neuroinflammation and oxidative stress are central events. Recent ...
Article
Icon

TET2 Regulates the Neuroinflammatory Response in Microglia

Carrillo Jiménez, Alejandro; Ruiz Laza, Rocío; García Domínguez, Irene; García Revilla, Juan; Espinosa Oliva, Ana María; Venero Recio, José Luis; Burguillos García, Miguel Ángel; Tayara, Khadija (Elsevier, 2019-01-01)
Epigenomic mechanisms regulate distinct aspects of the inflammatory response in immune cells. Despite the central role for ...
Article
Icon

Brainiac Caspases: Beyond the Wall of Apoptosis

Espinosa Oliva, Ana María; García Revilla, Juan; Alonso Bellido, Isabel María; Burguillos García, Miguel Ángel (Frontiers Media, 2019-01-01)
For the last two decades, caspases, a family of cysteine-aspartic proteases, have evolved from being considered solely as ...
Article
Icon

Magnetofection as a new tool to study microglia biology

Venero Recio, José Luis; Burguillos García, Miguel Ángel (Medknow Publications, 2019-01-01)
PhD Thesis
Icon

Papel de la galectina-3 en la respuesta inmune y en la pérdida neuronal asociada a un modelo murino de daño cerebral traumático.

Burguillos García, Miguel Ángel; Venero Recio, José Luis; Carrillo Jiménez, Alejandro (2018-07-13)
La lesión cerebral traumática (TBI) es actualmente una causa importante de muerte y discapacidad en la sociedad occidental, ...
Article
Icon

Effective Knockdown of Gene Expression in Primary Microglia With siRNA and Magnetic Nanoparticles Without Cell Death or Inflammation

Carrillo Jiménez, Alejandro; Puigdellívol, Mar; Vilalta, Anna; Venero Recio, José Luis; Brown, Charles Guy; Burguillos García, Miguel Ángel (Frontiers Media, 2018-01-01)
Microglia, the resident immune cells of the brain, have multiple functions in physiological and pathological conditions, ...
Article
Icon

Galectin-3 released in response to traumatic brain injury acts as an alarmin orchestrating brain immune response and promoting neurodegeneration

Kei Yip, Ping; Carrillo Jiménez, Alejandro; King, Paul; Vilalta, Anna; Venero Recio, José Luis; Burguillos García, Miguel Ángel (Nature, 2017-01-01)
Traumatic brain injury (TBI) is currently a major cause of morbidity and poor quality of life in Western society, with an ...
Article
Icon

Spatio-temporal activation of caspase-8 in myeloid cells upon ischemic stroke

Rodhe, Johanna; Burguillos García, Miguel Ángel; Martínez de Pablos, Rocío; Kavanagh, Edel T.; Persson, Annette; Englund, Elisabet; Venero Recio, José Luis (BioMed Central, 2016-01-01)
Ischemic stroke (caused by thrombosis, embolism or vasoconstriction) lead to the recruitment and activation of immune cells ...
PhD Thesis
Icon

A dual tool. The role of the ripoptosome in phagocytic cell activation and differentiation

Venero Recio, José Luis; Burguillos García, Miguel Ángel; Oliva Martín, María José (2015-10-19)
El término ripoptosoma hace referencia a la plataforma molecular que contiene, entre otras, dos proteínas implicadas en ...
Article
Icon

Microglia-secreted galectin-3 acts as a toll-like receptor 4 ligand and contributes to microglial activation

Burguillos García, Miguel Ángel; Svensson, Martina; Schulte, Tim; Boza Serrano, Antonio; García Quintanilla, Alberto; Kavanagh, Edel T.; Santiago Pavón, Martiniano; Viceconte, Nikenza; Oliva Martín, María José; Osman, Ahmed Mohamed; Salomonsson, Emma; Amar, Lahouari; Persson, Annette; Blomgren, Klas; Achour, Adnane; Englund, Elisabet; Leffler, Hakon; Venero Recio, José Luis; Joseph, Bertrand; Deierborg, Tomas (2015-01-01)
Inflammatory response induced by microglia plays a critical role in the demise of neuronal populations in neuroinflammatory ...
Article
Icon

Deletion of caspase-8 in mouse myeloid cells blocks microglia pro-inflammatory activation and confers protection in MPTP neurodegeneration model

Kavanagh, Edel T.; Burguillos García, Miguel Ángel; Carrillo Jiménez, Alejandro; Oliva Martín, María José; Santiago Pavón, Martiniano; Rodhe, Johanna; Joseph, Bertrand; Venero Recio, José Luis (Impact Journals, LLC, 2015-01-01)
Increasing evidence involves sustained pro-inflammatory microglia activation in the pathogenesis of different neurodegenerative ...
Article
Icon

Neuromelanin activates proinflammatory microglia through a caspase-8-dependent mechanism

Viceconte, Nikenza; Burguillos García, Miguel Ángel; Herrera Carmona, Antonio José; Martínez de Pablos, Rocío; Joseph, Bertrand; Venero Recio, José Luis (BioMed Central, 2015-01-01)
Background We have uncovered a caspase-dependent (caspase-8/caspase-3/7) signaling governing microglia activation and ...
Article
Icon

Regulation of caspase-3 processing by cIAP2 controls the switch between pro-inflammatory activation and cell death in microglia

Kavanagh, Edel T.; Rodhe, Johanna; Burguillos García, Miguel Ángel; Venero Recio, José Luis; Joseph, Bertrand (Nature Publishing Group, 2014-01-01)
The activation of microglia, resident immune cells of the central nervous system, and inflammation-mediated neurotoxicity ...
Article
Icon

The role of Galectin-3 in α-synuclein-induced microglial activation

Boza Serrano, Antonio; Reyes, Juan F.; Rey, Nolwen L.; Leffler, Hakon; Bousset, Luc; Nilsson, Ulf J.; Brundin, Patrik; Venero Recio, José Luis; Burguillos García, Miguel Ángel; Deierborg, Tomas (BioMed Central, 2014-01-01)
Background: Parkinson ’ s disease (PD) is the most prevalent neurodegenerative motor disorder. The neuropathology ...
PhD Thesis
Icon

Biochemical and molecular bases of the cell death in the neuroinflammatory of Parkinson's disease induced by LPS

Venero Recio, José Luis; Burguillos García, Miguel Ángel (2009-01-01)