Perfil del autor: Roodveldt, Cintia
Datos institucionales
Nombre | Roodveldt, Cintia |
Departamento | Bioquímica Médica y Biología Molecular e Inmunología |
Área de conocimiento | Bioquímica y Biología Molecular |
Categoría profesional | Profesora Titular de Universidad |
Correo electrónico | Solicitar |
Estadísticas
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Nº publicaciones
14
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Nº visitas
3328
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Nº descargas
3364
Publicaciones |
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Tesis Doctoral
Mecanismos modulatorios de MOK en la regulación de la respuesta inflamatoria de la microglía en ELA
(2024)
La esclerosis lateral amiotrófica (ELA) es una enfermedad neurodegenerativa actualmente incurable que, en el momento del ... |
Artículo
MAPK/MAK/MRK overlapping kinase (MOK) controls microglial inflammatory/type- I IFN responses via Brd4 and is involved in ALS
(National Academy of Sciences, 2023)
Amyotrophic lateral sclerosis (ALS) is a fatal and incurable neurodegenerative disease affecting motor neurons and ... |
Artículo
Immune signaling kinases in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD)
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
Amyotrophic lateral sclerosis (ALS) is the most common neurodegenerative disorder of motor neurons in adults, with a median ... |
Artículo
Distinct responses of human peripheral blood cells to different misfolded protein oligomers
(Wiley-Blackwell, 2021)
Increasing evidence indicates that peripheral immune cells play a prominent role in neurodegeneration connected to protein ... |
Tesis Doctoral |
Artículo
Differential Interactome and Innate Immune Response Activation of Two Structurally Distinct Misfolded Protein Oligomers
(American Chemical Society, 2019)
The formation of misfolded protein oligomers during early stages of amyloid aggregation and the activation of neuroinflammatory ... |
Artículo
Immunization with α-synuclein/Grp94 reshapes peripheral immunity and suppresses microgliosis in a chronic parkinsonism model
(Wiley, 2018)
Neuroinflammation mediated by chronically activated microglia, largely caused by abnormal accumulation of misfolded ... |
Tesis Doctoral
Alpha-synuclein and immune system crosstalk in parkinson's disease; therapeutic approaches of its modulation by molecular chaperones
(2017)
This Doctoral Thesis is focused on the interplay between the immune system and the Parkinson’s related protein alpha-Synuclein. ... |
Artículo
Editorial: Molecular chaperones and neurodegeneration
(Frontiers Media, 2017)
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Artículo
Commentary: Immunochemical Markers of the Amyloid Cascade in the Hippocampus in Motor Neuron Diseases
(Frontiers Media, 2017)
In case we needed reminding, age-related neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease ... |
Artículo
The chaperonin CCT inhibits assembly of α-synuclein amyloid fibrils by a specific, conformation-dependent interaction
(Nature Publishing Group, 2017)
The eukaryotic chaperonin CCT (chaperonin containing TCP-1) uses cavities built into its double-ring structure to encapsulate ... |
Tesis Doctoral
Esclerosis lateral amiotrófica: investigaciones en el modelo sod1g93a y correlaciones de interés clínico
(2016)
La esclerosis lateral amiotrófica (ELA) es una enfermedad neurodegenerativa, incurable y de carácter fatal en un plazo de ... |
Artículo
Preconditioning of Microglia by α-Synuclein Strongly Affects the Response Induced by Toll-like Receptor (TLR) Stimulation
(PLOS, 2013)
In recent years, it has become accepted that α-synuclein (αSyn) has a key role in the microglia-mediated neuroinflammation, ... |
Artículo |