Listar Artículos (Química Orgánica y Farmacéutica) por agencia financiadora "Ministerio de Ciencia, Innovación y Universidades (MICINN). España"
Mostrando ítems 1-18 de 18
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A comparative study of the antiangiogenic activity of hydroxytyrosyl alkyl ethers
(Elsevier, 2020)The phenolic compound hydroxytyrosol and its derivatives are responsible for some of the health benefits of the intake of ...
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Antimicrobial Properties of Amino-Acid-Derived N-Heterocyclic Carbene Silver Complexes
(MDPI, 2022)Complexes {Ag[NHCMes,R]}n (R = H, 2a; Me, 2b and 2b’; iPr, 2c; iBu, 2d), were prepared by treatment of imidazolium precursor ...
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Apolar carbohydrates as DNA capping agents
(Royal Society of Chemistry, 2012)Mono- and disaccharides have been shown to stack on top of DNA duplexes stabilizing sequences with terminal C–G base pairs. ...
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Biodegradable double cross-linked chitosan hydrogels for drug delivery: Impact of chemistry on rheological and pharmacological performance
(Elsevier, 2020-12)This study investigates the impact of dual ionic and covalent cross-links (ion-XrL and cov-XrL) on the properties of ...
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Biological Evaluation of Carbohydrate-based Aprepitant Analogs for Neuroblastoma Treatment
(Elsevier, 2024)Different studies using Aprepitant, a NK1R antagonist currently used as a clinical drug for treating chemotherapy-related ...
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Biologically Relevant Micellar Nanocarrier Systems for Drug Encapsulation and Functionalization of Metallic Nanoparticles
(MDPI, 2022)The preparation of new and functional nanostructures has received more attention in the scientific community in the past ...
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Carbohydrate-DNA interactions at G-quadruplexes: Folding and stability changes by attaching sugars at the 5′-End
(Wiley-Blackwell, 2013)Quadruplex DNA structures are attracting an enormous interest in many areas of chemistry, ranging from chemical biology, ...
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Different effects of low selenite and selenium-nanoparticle supplementation on adipose tissue function and insulin secretion in adolescent male rats
(MDPI, 2022)Adolescence is a period of intense growth and endocrine changes, and obesity and insulin-resistance processes during this ...
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Enantioselective synthesis of 4-amino-3,4-dihydrocoumarins and their non-cyclic hydroxyester precursors: Biological evaluation for the treatment of glioblastoma multiforme
(Elsevier, 2022)The stereoselective addition of ethyl acetate enolate to the C═N bond of N-tert-butylsulfinylimines has been investigated ...
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Homochiral imidazolium-based dicarboxylate silver(i) compounds: synthesis, characterisation and antimicrobial properties
(Royal Society of Chemistry, 2022-03)Complexes [Ag(LR)], 2 (LR = 2,2′-(imidazolium-1,3-diyl)di(2-alkylacetate)), were prepared by treatment of compounds HLR, ...
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Immunomodulatory Effects of (R)-Sulforaphane on LPS-Activated Murine Immune Cells: Molecular Signaling Pathways and Epigenetic Changes in Histone Markers
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)The aim of this study was to explore the immunomodulatory effects of the natural enantiomer (R)-Sulforaphane (SFN) and the ...
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In-Depth Study into Polymeric Materials in Low-Density Gastroretentive Formulations
(MDPI, 2020)The extensive use of oral dosage forms for the treatment of diseases may be linked to deficient pharmacokinetic properties. ...
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Magnetic Nanoparticles as MRI Contrast Agents
(Springer, 2020)Iron oxide nanoparticles (IONPs) have emerged as a promising alternative to conventional contrast agents (CAs) for magnetic ...
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Microbiota-liver-bile salts axis, a novel mechanism involved in the contrasting effects of sodium selenite and selenium-nanoparticle supplementation on adipose tissue development in adolescent rats
(MDPI, 2023)Adolescence is a period during which body composition changes deeply. Selenium (Se) is an excellent antioxidant trace ...
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Nanocomposites of Microbial Polyglutamic Acid and Nanoclays Compatibilized by Organophosphonium Surfactants
(Wiley, 2018)Ionic coupling of bacterial poly(γ-glutamic acid) (PGGA) with alkyltrimethylphosphonium surfactants is reported to render ...
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Piperazine-derived small molecules as potential Flaviviridae NS3 protease inhibitors. In vitro antiviral activity evaluation against Zika and Dengue viruses
(Elsevier, 2023)Since 2011 Direct Acting antivirals (DAAs) drugs targeting different non-structural (NS) viral proteins (NS3, NS5A or NS5B ...
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(R)-8-Methylsulfinyloctyl isothiocyanate from Nasturtium officinale inhibits LPS-induced immunoinflammatory responses in mouse peritoneal macrophages: chemical synthesis and molecular signaling pathways involved
(Royal Society of Chemistry, 2023-07-20)The aim of this study was to develop an optimal synthetic route to obtain natural (R)-8-methylsulfinyloctyl isothiocyanate ...
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Synthesis and characterization of enantiopure chiral NH2/SO palladium complexes
(Royal Society of Chemistry, 2023)A series of enantiopure chiral NH2/SO palladium complexes have been synthesised with high yields by treating the corresponding ...