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Mostrando ítems 31-40 de 172
Artículo
Glycodendritic structures: Tools to interact with DC-SIGN
(Universidade de São Paulo, 2013)
The key role of carbohydrates in many biological events has attracted the interest of the scientific community. This fact has demanded the access to new tools necessary to understand this role and the interaction of ...
Artículo
Asymmetric organocatalytic synthesis of tertiary azomethyl alcohols: key intermediates towards azoxy compounds and α-hydroxy-β-amino esters
(Royal Society of Chemistry (Great Britain), 2017)
A series of peracylated glycosamine-derived thioureas have been synthesized and their behavior as bifunctional organocatalysts has been tested in the enantioselective nucleophilic addition of formaldehyde tert-butyl hydrazone ...
Artículo
Cationic Platinum(II) σ-SiH Complexes in Carbon Dioxide Hydrosilation
(John Wiley & Sons, 2016)
The low-electron-count cationic platinum complex [Pt(ItBu’)(ItBu)][BAr], 1, interacts with primary and secondary silanes to form the corresponding σ-SiH complexes. According to DFT calculations, the most stable coordination ...
Artículo
LPS promotes Th2 dependent sensitisation leading to anaphylaxis in a Pru p 3 mouse model
(Nature Publishing Group, 2017-01-13)
Pru p 3 is the major peach allergen in the Mediterranean area. It frequently elicits severe reactions, limiting its study in humans, raising the need for animal models to investigate the immunological mechanisms involved. ...
Artículo
Trehalose- and Glucose-Derived Glycoamphiphiles: Small-Molecule and Nanoparticle Toll-Like Receptor 4 (TLR4) Modulators
(American Chemical Society, 2014)
An increasing number of pathologies have been linked to Toll-like receptor 4 (TLR4) activation and signaling, therefore new hit and lead compounds targeting this receptor activation process are urgently needed. We report ...
Artículo
A Diels–Alder Reaction Triggered by a [4 + 3] Metallacycloaddition
(American Chemical Society, 2015)
The TpMe2Ir(III) complex 1-OH2 (TpMe2 = hydrotris(3,5-dimethylpyrazolyl)borate), which contains a labile molecule of water and an iridium-bonded alkenyl moiety (−C(R)═C(R)–(R=CO2Me)) as part of a benzo-annulated five-membered ...
Artículo
Synthesis and Reactivity of Nickel an Palladium Fluoride Complexes with PCP Pincer Ligands. A NMR-Based Assessment of Electron-Donating Properties of Fluoride and Other Monoanionic Ligands
(American Chemical Society, 2012)
A series of complexes of the type [(iPrPCP)M-L] (M = Ni, Pd), containing the 2,6-bis(diisopropylphosphinomethyl)phenyl (iPrPCP) pincer ligand and simple monoanionic ligands L (F, Cl, Br, H, Me, Ph, NO3, and OTf), have been ...
Artículo
Molecular Determinants for Cyclo-oligosaccharide-based Nanoparticle-mediated Effective siRNA Transfection
(Future Medicine Ltd., 2017)
Aim: To study the structural requirements that a cyclooligosaccharide-based nanoparticle must fulfill to be an efficient siRNA transfection vector. Materials & methods: siRNA protection from degradation by RNAses, transfection ...
Artículo
Synthesis, properties, and some rhodium, iridium, and platinum complexes of a series of bulky m-terphenylphosphine ligands
(Elsevier, 2016)
A series of sterically demanding aryl phosphine ligands (L) bearing terphenyl substituents, PR2Ar′ (R = hydrocarbyl, Ar′ = 2,6-diarylphenyl radical) has been prepared and characterized. The stability of these ligands towards ...
Artículo
Alkoxyamine-cyanoborane adducts: Efficient cyanoborane transfer agents
(Royal Society of Chemistry, 2011)
We report the synthesis of the hitherto unknown zwitterionic alkoxyamino cyanoboranes by reduction of O-alkyloximes with sodium cyanoborohydride; unprecedented cyanoboronated N-alkoxyformamidines were also isolated as ...