- idUS
- Listar por autor
Listar por autor "Rubio Contreras, Diana"
Mostrando ítems 1-5 de 5
-
Artículo
Canonical non-homologous end-joining promotes genome mutagenesis and translocations induced by transcription-associated DNA topoisomerase 2 activity
Olmedo Pelayo, Joaquín; Rubio Contreras, Diana; Gómez Herreros, Fernando (Oxford University Press, 2020)DNA topoisomerase II (TOP2) is a major DNA metabolic enzyme, with important roles in replication, transcription, chromosome ...
-
Tesis Doctoral
Genome Instability Associated with DNA Topoisomerase Activity during Gene Transcription
Rubio Contreras, Diana (2023-07-07)Las lesiones que se producen en el ADN suponen un desafío continuo para la integridad genómica, siendo las roturas de ...
-
Artículo
Genome-scale mapping of DNA damage suppressors through phenotypic CRISPR-Cas9 screens
Zhao, Yichao; Tabet, Daniel; Rubio Contreras, Diana; Lao, Linjiang; Kousholt, Arne Nedergaard; Weile, Jochen; Gómez Herreros, Fernando; Durocher, Daniel (Cell Press, 2023-08-03)To maintain genome integrity, cells must accurately duplicate their genome and repair DNA lesions when they occur. To ...
-
Artículo
Human Omental Mesothelial Cells Impart an Immunomodulatory Landscape Impeding B- and T-Cell Activation
Gauthier, Benoit R.; Rubio Contreras, Diana; Gómez Rosado, Juan Carlos; Capitán Morales, Luis Cristobal; Hmadcha, Abdelkrim; Soria, Bernat; Lachaud, Christian Claude (MDPI, 2022)Mesothelial cells form the mesothelium, a simple epithelium lining the walls of serous cavities and the surface of visceral ...
-
Artículo
TDP1 suppresses chromosomal translocations and cell death induced by abortive TOP1 activity during gene transcription
Rubio Contreras, Diana; Gómez Herreros, Fernando (Nature Research, 2023-11-09)DNA topoisomerase I (TOP1) removes torsional stress by transiently cutting one DNA strand. Such cuts are rejoined by TOP1 ...