Chapter of Book
Modeling Signal Transduction Using P Systems
Author/s | Paun, Andrei
Pérez Jiménez, Mario de Jesús Romero Campero, Francisco José |
Department | Universidad de Sevilla. Departamento de Ciencias de la Computación e Inteligencia Artificial |
Publication Date | 2006 |
Deposit Date | 2017-02-03 |
Published in |
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ISBN/ISSN | 978-3-540-69088-7 0302-9743 |
Abstract | Cellular signalling pathways are fundamental to the control
and regulation of cell behavior. Understanding of biosignalling network
functions is crucial to the study of different diseases and to the design
of effective ... Cellular signalling pathways are fundamental to the control and regulation of cell behavior. Understanding of biosignalling network functions is crucial to the study of different diseases and to the design of effective therapies. In this paper we present P systems as a feasible computational modeling tool for cellular signalling pathways that takes into consideration the discrete character of the components of the system and the key role played by membranes in their functioning. We illustrate these cellular models simulating the epidermal growth factor receptor (EGFR) signalling cascade and the FAS–induced apoptosis using a deterministic strategy for the evolution of P systems. |
Funding agencies | Ministerio de Educación y Ciencia (MEC). España Junta de Andalucía |
Project ID. | TIN2005-09345-C04-01
TIC-581 |
Citation | Paun, A., Pérez Jiménez, M.d.J., y Romero Campero, F.J. (2006). Modeling Signal Transduction Using P Systems. En Membrane Computing. WMC 2006. Lecture Notes in Computer Science, vol 4361 (pp. 100-122). Berlin: Springer. |
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