Article
Continuum Modeling and Simulation in Bone Tissue Engineering
Author/s | Sanz Herrera, José Antonio
Reina Romo, Esther |
Department | Universidad de Sevilla. Departamento de Mecánica de Medios Continuos y Teoría de Estructuras Universidad de Sevilla. Departamento de Ingeniería Mecánica y de Fabricación |
Publication Date | 2019-09 |
Deposit Date | 2020-01-22 |
Published in |
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Abstract | Bone tissue engineering is currently a mature methodology from a research perspective.
Moreover, modeling and simulation of involved processes and phenomena in BTE have been proved
in a number of papers to be an excellent ... Bone tissue engineering is currently a mature methodology from a research perspective. Moreover, modeling and simulation of involved processes and phenomena in BTE have been proved in a number of papers to be an excellent assessment tool in the stages of design and proof of concept through in-vivo or in-vitro experimentation. In this paper, a review of the most relevant contributions in modeling and simulation, in silico, in BTE applications is conducted. The most popular in silico simulations in BTE are classified into: (i) Mechanics modeling and sca old design, (ii) transport and flow modeling, and (iii) modeling of physical phenomena. The paper is restricted to the review of the numerical implementation and simulation of continuum theories applied to di erent processes in BTE, such that molecular dynamics or discrete approaches are out of the scope of the paper. Two main conclusions are drawn at the end of the paper: First, the great potential and advantages that in silico simulation o ers in BTE, and second, the need for interdisciplinary collaboration to further validate numerical models developed in BTE. |
Project ID. | DPI2017-82501-P |
Citation | Sanz Herrera, J.A. y Reina Romo, E. (2019). Continuum Modeling and Simulation in Bone Tissue Engineering. Applied Sciences, 9 (18). Article number 3674. |
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