Article
Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways
Author/s | Klein, Hannah L.
Bačinskaja, Giedré Che, Jun Cheblal, Anais Elango, Rajula Epshtein, Anastasiya Fitzgerald, Devon M. Gómez González, Belén Khan, Sharik R. Kumar, Sandeep Mothish Leland, Bryan A. Marie, Léa Aguilera López, Andrés |
Department | Universidad de Sevilla. Departamento de Genética |
Publication Date | 2019 |
Deposit Date | 2019-05-16 |
Published in |
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Abstract | Understanding the plasticity of genomes has been greatly aided by assays for recombination, repair and mutagenesis. These assays have been developed in microbial systems that provide the advantages of genetic and molecular ... Understanding the plasticity of genomes has been greatly aided by assays for recombination, repair and mutagenesis. These assays have been developed in microbial systems that provide the advantages of genetic and molecular reporters that can readily be manipulated. Cellular assays comprise genetic, molecular, and cytological reporters. The assays are powerful tools but each comes with its particular advantages and limitations. Here the most commonly used assays are reviewed, discussed, and presented as the guidelines for future studies. |
Project ID. | ERC2014-ADG669898 TARLOOP
BFU2016-75058-P BIO1238 |
Citation | Klein, H.L., Bačinskaja, G., Che, J., Cheblal, A., Elango, R., Epshtein, A.,...,Aguilera López, A. (2019). Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways. Microbial Cell, 6 (1), 1-64. |
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