Article
A microscopy technique based on bio-impedance sensors
Author/s | Yúfera García, Alberto
Huertas Sánchez, Gloria Olmo Fernández, Alberto |
Department | Universidad de Sevilla. Departamento de Tecnología Electrónica |
Publication Date | 2012 |
Deposit Date | 2018-06-29 |
Published in |
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Abstract | It is proposed a microscopy for cell culture applications based on impedance sensors. The imagined signals are measured with the Electrical Cell-Substrate Spectroscopy (ECIS) technique, by identifying the cell area. The ... It is proposed a microscopy for cell culture applications based on impedance sensors. The imagined signals are measured with the Electrical Cell-Substrate Spectroscopy (ECIS) technique, by identifying the cell area. The proposed microscopy allows real-time monitoring inside the incubator, reducing the contamination risk by human manipulation. It requires specific circuits for impedance measurements, a two-dimensional sensor array (pixels), and employing electrical models to decode efficiently the measured signals. Analogue Hardware Description Language (AHDL) circuits for cell-microelectrode enables the use of geometrical and technological data into the system design flow. A study case with 8x8 sensor array is reported, illustrating the evolution and power of the proposed image acquisition. |
Funding agencies | Junta de Andalucía |
Project ID. | P0-TIC-5386 |
Citation | Yúfera García, A., Huertas Sánchez, G. y Olmo Fernández, A. (2012). A microscopy technique based on bio-impedance sensors. Procedia Engineering, 47, 1049-1052. |
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