Presentation
A CMOS Tracking System Approach for Cell Motility Assays
Author/s | Martínez Gómez, Cristina
Olmo Fernández, Alberto ![]() ![]() ![]() ![]() ![]() ![]() ![]() Huertas Sánchez, Gloria ![]() ![]() ![]() ![]() ![]() ![]() ![]() Pérez García, Pablo ![]() ![]() ![]() ![]() ![]() ![]() ![]() Maldonado-Jacobi, Andrés Yúfera García, Alberto ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
Department | Universidad de Sevilla. Departamento de Tecnología Electrónica Universidad de Sevilla. Departamento de Electrónica y Electromagnetismo |
Publication Date | 2017 |
Deposit Date | 2018-06-12 |
Published in |
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ISBN/ISSN | 978-989-758-216-5 |
Abstract | This work proposes a method for studying and monitoring in real-time a single cell on a 2D electrode
matrix, of great interest in cell motility assays and in the characterization of cancer cell metastasis. A CMOS
system ... This work proposes a method for studying and monitoring in real-time a single cell on a 2D electrode matrix, of great interest in cell motility assays and in the characterization of cancer cell metastasis. A CMOS system proposal for cell location based on occupation maps data generated from Electrical Cell-substrate Impedance Spectroscopy (ECIS) has been developed. From this cell model, obtained from experimental assays data, an algorithm based on analysis of the 8 nearest neighbors has been implemented, allowing the evaluation of the cell center of mass. The path followed by a cell, proposing a Brownian route, has been simulated with the proposed algorithm. The presented results show the success of the approach, with accuracy over 95% in the determination of any coordinate (x, y) from the expected center of mass. |
Funding agencies | Ministerio de Economía y Competitividad (MINECO). España |
Project ID. | TEC2013-46242-C3-1-P
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Citation | Martínez Gómez, C., Olmo Fernández, A., Huertas Sánchez, G., Pérez García, P., Maldonado Jacobi, A. y Yúfera García, A. (2017). A CMOS Tracking System Approach for Cell Motility Assays. En BIOSTEC 2017: 10th International Joint Conference on Biomedical Engineering Systems and Technologies (229-236), Porto, Portugal: SciTePress Digital Library. |
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