Article
1,2,3-Triazoles from carbonyl azides and alkynes: filling the gap
Author/s | Haldón, Estela
Álvarez González, Eleuterio Nicasio Jaramillo, María del Carmen Pérez, Pedro J. |
Department | Universidad de Sevilla. Departamento de Química Inorgánica |
Publication Date | 2014 |
Deposit Date | 2017-09-13 |
Published in |
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Abstract | Electron deficient azides are challenging substrates in CuAAC reactions. Particularly, when N-carbonyl azides are applied the formation of N-carbonyl triazoles has not yet been observed. We report herein the first example ... Electron deficient azides are challenging substrates in CuAAC reactions. Particularly, when N-carbonyl azides are applied the formation of N-carbonyl triazoles has not yet been observed. We report herein the first example of this class of reaction, with a copper-based system that efficiently enables the synthesis of N-carbamoyl 1,2,3-triazoles by [3+2] cycloaddition of N-carbamoyl azides and alkynes |
Funding agencies | Ministerio de Economía y Competitividad (MINECO). España Junta de Andalucía |
Project ID. | info:eu-repo/grantAgreement/MINECO/CTQ2011-28942-CO2-01
info:eu-repo/grantAgreement/MINECO/CTQ2011-27033 P07-FQM-02745 P10-FQM-06292 |
Citation | Haldón, E., Álvarez, E., Nicasio, M.C. y Pérez, P.J. (2014). 1,2,3-Triazoles from carbonyl azides and alkynes: filling the gap. Chemical Communications, 50, 8978-8981. |
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