Article
Arabidopsis thaliana telomeres exhibit euchromatic features
Author/s | Vaquero Sedas, María Isabel
Gámez Arjona, Francisco M. Vega Palas, Miguel Ángel |
Department | Universidad de Sevilla. Departamento de Bioquímica Vegetal y Biología Molecular |
Publication Date | 2011 |
Deposit Date | 2017-04-11 |
Published in |
|
Abstract | Telomere function is influenced by chromatin structure and organization, which usually involves epigenetic modifications. We describe here the chromatin structure of Arabidopsis thaliana telomeres. Based on the study of ... Telomere function is influenced by chromatin structure and organization, which usually involves epigenetic modifications. We describe here the chromatin structure of Arabidopsis thaliana telomeres. Based on the study of six different epigenetic marks we show that Arabidopsis telomeres exhibit euchromatic features. In contrast, subtelomeric regions and telomeric sequences present at interstitial chromosomal loci are heterochromatic. Histone methyltransferases and the chromatin remodeling protein DDM1 control subtelomeric heterochromatin formation. Whereas histone methyltransferases are required for histone H3K9 2Me and non-CpG DNA methylation, DDM1 directs CpG methylation but not H3K9 2Me or non-CpG methylation. These results argue that both kinds of proteins participate in different pathways to reinforce subtelomeric heterochromatin formation. |
Funding agencies | Ministerio de Educación y Ciencia (MEC). España |
Project ID. | BFU2004-01560/BMC
BFU2008-02497/BMC GEN2003-20859-C03-03/INTER |
Citation | Vaquero Sedas, M.I., Gámez Arjona, F.M. y Vega Palas, M.Á. (2011). Arabidopsis thaliana telomeres exhibit euchromatic features. Nucleic Acids Research, 39 (6), 2007-2017. |
Files | Size | Format | View | Description |
---|---|---|---|---|
Arabidopsis.pdf | 3.140Mb | [PDF] | View/ | |