Article
Silver-free gold-catalyzed heterocyclizations through intermolecular H-bonding activation.
Author/s | Elías Rodríguez, María del Pilar
Matador Martínez, Esteban ![]() ![]() ![]() ![]() ![]() ![]() Benítez Narváez, Manuel Tejero, Tomás Díez Martín, Elena ![]() ![]() ![]() ![]() ![]() ![]() ![]() Fernández Fernández, Rosario Fátima ![]() ![]() ![]() ![]() ![]() ![]() ![]() Monge Fernández, David ![]() ![]() ![]() ![]() ![]() ![]() ![]() Lassaletta, José M. |
Department | Universidad de Sevilla. Departamento de Química orgánica |
Publication Date | 2023-01-27 |
Deposit Date | 2024-05-23 |
Published in |
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Abstract | Modulable monosulfonyl squaramides have been shown to exert activation of gold(I) chloride complexes through H-bonding in an intermolecular way. Combinations of (PPh3)AuCl or IPrAuCl complexes and an optimal sulfonyl ... Modulable monosulfonyl squaramides have been shown to exert activation of gold(I) chloride complexes through H-bonding in an intermolecular way. Combinations of (PPh3)AuCl or IPrAuCl complexes and an optimal sulfonyl squaramidecocatalyst bearing two 3,5-bis(trifluoromethyl)phenyl groups efficiently catalyzed diverse heterocyclizations and a cyclopropanationreaction, avoiding in all cases undesired side reactions. Computational studies indicate that the Au−Cl bond breaks by transligationto the triple bond in a ternary complex formed by the actual AuCl···HBD catalyst and the substrate. |
Funding agencies | Ministerio de Ciencia e Innovación (MICIN). España European Commission (EC). Fondo Europeo de Desarrollo Regional (FEDER) Junta de Andalucía Gobierno regional de Aragón |
Project ID. | PID2019-106358GB-C21
![]() PID2019-106358GBC22 ![]() PID2019-104090RB-100 ![]() MSALAS-2022-19993 ![]() P18-FR-3531 ![]() P18- FR-644 ![]() US-1262867 ![]() DOC_00749 ![]() |
Citation | Elías Rodríguez, M.d.P., Matador Martínez, E., Benítez Narváez, M., Tejero, T., Díez Martín, E., Fernández Fernández, R.F.,...,Lassaletta, J.M. (2023). Silver-free gold-catalyzed heterocyclizations through intermolecular H-bonding activation.. Journal of Organic Chemistry, 88 (4), 2487-2492. https://doi.org/10.1021/acs.joc.2c02932. |
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