Article
Mobile Laboratory Unit: A disruptor solution for hemostasis management during major surgery. Usage in the context of face transplantation
Author/s | León Justel, Antonio
Noval-Padillo, Jose Angel Polonio, Franciso Gomez-Cia, Tomas Hinojosa, Rafael Porras, Manuel Guerrero Montávez, Juan Miguel |
Department | Universidad de Sevilla. Departamento de Bioquímica Médica y Biología Molecular e Inmunología |
Publication Date | 2012 |
Deposit Date | 2024-03-18 |
Published in |
|
Abstract | Background: The management of surgical bleeding during
a face transplant in a patient diagnosed with bilateral neurofi bromatosis is quite complex. With the actual methods and
technology for hemostasis management, it may ... Background: The management of surgical bleeding during a face transplant in a patient diagnosed with bilateral neurofi bromatosis is quite complex. With the actual methods and technology for hemostasis management, it may not always be possible to give the clinician the support needed to manage operative associated bleeding. Bedside hemostasis monitors are needed urgently to assist clinicians in making the correct diagnosis in a timely manner. Methods: Our Mobile Laboratory Unit is a disruptive solution for hemostasis management during major surgery as it allows real-time monitoring, the predominant mechanism of bleeding and goal-direct coagulation therapy. The unit is an autonomous mobile platform that can be moved immediately to anywhere its service is needed and offers a complete fl exible laboratory test which includes biochemistry, hematology and coagulation studies as standard equipment. Results: In our case the test performed by the unit allowed us to identify the reason for our patient ’ s bleeding at the bedside. Severely decreased clot fi rmness of the fi brin-based clot and a less impaired fi rmness of the whole blood clot, suggested an acceptable contribution of platelets to the clot quality, but decreased polymerization of fi brinogen into fi brin. Conclusions: In our opinion new insights into the pathophysiology of coagulopathy, the availability of technology such as our Mobile Laboratory Unit, and awareness of side effects of intravenous fl uids should encourage the idea that perhaps it is time to change hemostasis management in operationrelated bleeding. |
Citation | León Justel, A., Noval-Padillo, J.A., Polonio, F., Gomez-Cia, T., Hinojosa, R., Porras, M. y Guerrero Montávez, J.M. (2012). Mobile Laboratory Unit: A disruptor solution for hemostasis management during major surgery. Usage in the context of face transplantation. Clinical Chemistry and Laboratory Medicine, 50 (9), 1621-1624. https://doi.org/10.1515/cclm-2011-0764. |
Files | Size | Format | View | Description |
---|---|---|---|---|
Mobile Laboratory...pdf | 226.0Kb | [PDF] | View/ | |
This item appears in the following collection(s)
This document is protected by intellectual and industrial property rights. Without prejudice to existing legal exemptions, its reproduction, distribution, public communication or transformation is prohibited without the authorization of the rights holder, unless otherwise indicated.