Article
Strategies for the Biofunctionalization of Straining Flow Spinning Regenerated Bombyx mori Fibers
Author/s | Lozano Picazo, Paloma
Castro Domínguez, Cristina Bruno, Augusto Luis Baeza, Alejandro Martínez, Adelia S. López, Patricia A. Gañán-Calvo, Alfonso M. ![]() ![]() ![]() ![]() ![]() ![]() ![]() Pérez-Rigueiro, José |
Department | Universidad de Sevilla. Departamento de Ingeniería Aeroespacial y Mecánica de Fluidos |
Publication Date | 2022 |
Deposit Date | 2023-05-24 |
Published in |
|
Abstract | High-performance regenerated silkworm (Bombyx mori) silk fibers can be produced efficiently through the straining flow spinning (SFS) technique. In addition to an enhanced biocompat-ibility that results from the removal ... High-performance regenerated silkworm (Bombyx mori) silk fibers can be produced efficiently through the straining flow spinning (SFS) technique. In addition to an enhanced biocompat-ibility that results from the removal of contaminants during the processing of the material, regenerated silk fibers may be functionalized conveniently by using a range of different strategies. In this work, the possibility of implementing various functionalization techniques is explored, including the production of fluorescent fibers that may be tracked when implanted, the combination of the fibers with enzymes to yield fibers with catalytic properties, and the functionalization of the fibers with cell-adhesion motifs to modulate the adherence of different cell lineages to the material. When considered globally, all these techniques are a strong indication not only of the high versatility of-fered by the functionalization of regenerated fibers in terms of the different chemistries that can be employed, but also on the wide range of applications that can be covered with these functionalized fibers. |
Funding agencies | Ministerio de Ciencia e Innovación (MICIN). España Comunidad de Madrid. España |
Project ID. | PID2020-116403RB-I00
![]() 10.13039/501100011033 ![]() Neurocentro-B2017/BMD-3760 ![]() Tec4Bio-CM/P2018/NMT-4443 ![]() |
Citation | Lozano Picazo, P., Castro Domínguez, C., Bruno, A.L., Baeza, A., Martínez, A.S., López, P.A.,...,Pérez-Rigueiro, J. (2022). Strategies for the Biofunctionalization of Straining Flow Spinning Regenerated Bombyx mori Fibers. Molecules, 27 (13), 4146. https://doi.org/10.3390/molecules27134146. |
Files | Size | Format | View | Description |
---|---|---|---|---|
Molecules_2022_Lozano_Strategi ... | 2.663Mb | ![]() | View/ | |