Article
Pyridine–hydrazone ligands in enantioselective palladium-catalyzed Suzuki–Miyaura cross-couplings
Author/s | Álvarez Casao, Yolanda
Estepa, Beatriz Monge Fernández, David ![]() ![]() ![]() ![]() ![]() ![]() ![]() Ros, Abel Iglesias Sigüenza, Francisco Javier ![]() ![]() ![]() ![]() ![]() ![]() ![]() Álvarez, Eleuterio Fernández Fernández, Rosario Fátima ![]() ![]() ![]() ![]() ![]() ![]() ![]() Lassaletta, José M. |
Department | Universidad de Sevilla. Departamento de Química orgánica |
Publication Date | 2016 |
Deposit Date | 2022-11-10 |
Published in |
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Abstract | The geometries and coordination properties of modular pyridineehydrazone N,N-ligands containing C2-
symmetric trans-2,5-diphenylpyrrolidine and trans-2,5-diphenylpiperidine as the terminal dialkylamino
units have been ... The geometries and coordination properties of modular pyridineehydrazone N,N-ligands containing C2- symmetric trans-2,5-diphenylpyrrolidine and trans-2,5-diphenylpiperidine as the terminal dialkylamino units have been analyzed by X-ray diffraction analysis of [PdCl2(N,N)] complexes [(N,N)¼pyridine hy- drazone ligand]. In combination with Pd(OAc)2 as the precatalyst, these ligands provide high enantio- selectivities (up to 95:5 er) in asymmetric SuzukieMiyaura cross couplings of 2-methoxy-1-naphthyl bromides with 1-naphthyl and 2-tolyl boronic acids. |
Funding agencies | Ministerio de Economía y Competitividad (MINECO). España Junta de Andalucía |
Project ID. | TQ2013-48164-C2-1-P
![]() CTQ2013- 48164-C2-2-P ![]() CTQ2014-51912-REDC ![]() RYC-2013-12585 ![]() 2012/FQM 1078 ![]() |
Citation | Álvarez Casao, Y., Estepa, B., Monge Fernández, D., Ros, A., Iglesias Sigüenza, F.J., Álvarez, E.,...,Lassaletta, J.M. (2016). Pyridine–hydrazone ligands in enantioselective palladium-catalyzed Suzuki–Miyaura cross-couplings. Tetrahedron, 72 (34), 5184-5190. https://doi.org/10.1016/j.tet.2015.12.053. |
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