Article
Apolar carbohydrates as DNA capping agents
Author/s | Lucas Rodríguez, Ricardo
Vengut Climent, Empar Gómez Pinto, Irene Aviñó, Anna Eritja, Ramón González, Carlos Morales, Juan Carlos |
Department | Universidad de Sevilla. Departamento de Química Orgánica y Farmacéutica |
Publication Date | 2012 |
Deposit Date | 2022-07-12 |
Published in |
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Abstract | Mono- and disaccharides have been shown to stack on top of DNA duplexes stabilizing sequences with terminal C–G base pairs. Here we present an apolar version of glucose and cellobiose as new capping agents that stack on ... Mono- and disaccharides have been shown to stack on top of DNA duplexes stabilizing sequences with terminal C–G base pairs. Here we present an apolar version of glucose and cellobiose as new capping agents that stack on DNA increasing considerably its stability with respect to their natural polyhydroxylated mono- and disaccharide DNA conjugates. |
Funding agencies | Ministerio de Ciencia, Innovación y Universidades (MICINN). España Generalitat de Catalunya Instituto de Salud Carlos III |
Project ID. | CTQ2006-01123
CTQ2007-68014- C02-02 CTQ2009-13705 BFU2007-63287 2009/SGR/208 CB06_01_0019 |
Citation | Lucas Rodríguez, R., Vengut Climent, E., Gómez Pinto, I., Aviñó, A., Eritja, R., González, C. y Morales, J.C. (2012). Apolar carbohydrates as DNA capping agents. Chemical Communications, 48 (24), 2991-2993. |
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