Presentation
A NSGA-II Algorithm for the Residue-Residue Contact Prediction
Author/s | Márquez Chamorro, Alfonso Eduardo
![]() ![]() ![]() ![]() ![]() ![]() ![]() Divina, Federico Aguilar Ruiz, Jesús Salvador Bacardit, Jaume Asencio Cortés, Gualberto Santiesteban Toca, Cosme E. |
Department | Universidad de Sevilla. Departamento de Lenguajes y Sistemas Informáticos |
Publication Date | 2012 |
Deposit Date | 2022-05-19 |
Published in |
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ISBN/ISSN | 978-3-642-29065-7 0302-9743 |
Abstract | We present a multi-objective evolutionary approach to
predict protein contact maps. The algorithm provides a set of rules,
inferring whether there is contact between a pair of residues or not. Such
rules are based on a ... We present a multi-objective evolutionary approach to predict protein contact maps. The algorithm provides a set of rules, inferring whether there is contact between a pair of residues or not. Such rules are based on a set of specific amino acid properties. These properties determine the particular features of each amino acid represented in the rules. In order to test the validity of our proposal, we have compared results obtained by our method with results obtained by other classification methods. The algorithm shows better accuracy and coverage rates than other contact map predictor algorithms. A statistical analysis of the resulting rules was also performed in order to extract conclusions of the protein folding problem. |
Funding agencies | Junta de Andalucía Ministerio de Ciencia Y Tecnología (MCYT). España |
Project ID. | P07-TIC-02611
![]() TIN2007-68084-C02-00 ![]() |
Citation | Márquez Chamorro, A.E., Divina, F., Aguilar Ruiz, J.S., Bacardit, J., Asencio Cortés, G. y Santiesteban Toca, C.E. (2012). A NSGA-II Algorithm for the Residue-Residue Contact Prediction. En EvoBIO 2012: 10th European Conference on Evolutionary Computation, Machine Learning and Data Mining in Bioinformatics (234-244), Málaga, España: Springer. |
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