Article
Redox-control of chlorophyll biosynthesis mainly depends on thioredoxins
Author/s | Richter, Andreas S.
Pérez Ruiz, Juan Manuel ![]() ![]() ![]() ![]() ![]() ![]() ![]() Cejudo Fernández, Francisco Javier ![]() ![]() ![]() ![]() ![]() ![]() ![]() Grimm, Bernhard |
Department | Universidad de Sevilla. Departamento de Bioquímica Vegetal y Biología Molecular |
Publication Date | 2018 |
Deposit Date | 2022-02-21 |
Published in |
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Abstract | In order to maintain enzyme stability and activity, chloroplasts use two systems of thiol-disulfide reductases for the control of redox-dependent properties of proteins. Previous studies have revealed that plastid-localized ... In order to maintain enzyme stability and activity, chloroplasts use two systems of thiol-disulfide reductases for the control of redox-dependent properties of proteins. Previous studies have revealed that plastid-localized thioredoxins (TRX) and the NADPH-dependent thioredoxin reductase C (NTRC) are important for the reduction of cysteine residues of enzymes involved in chlorophyll synthesis. Very recently, it was shown that the pale green phenotype of the ntrc mutant is suppressed when the contents of 2-cysteine peroxiredoxins (2CP) A and B are decreased. Here, we show that suppression of the ntrc phenotype results from a recovery of wild-type-like redox control of chlorophyll biosynthesis enzymes in ntrc/2cp mutants. The presented results support the conclusion that TRXs rather than NTRC are the predominant reductases mediating the redox-regulation of these enzymes. |
Project ID. | DFG 936 17-1
![]() SFB/TRR 175 ![]() BIO2017-85195-C2-1-P ![]() |
Citation | Richter, A.S., Pérez Ruiz, J.M., Cejudo Fernández, F.J. y Grimm, B. (2018). Redox-control of chlorophyll biosynthesis mainly depends on thioredoxins. FEBS Letters, 592 (18), 3111-3115. |
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