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Article
Spatio-temporal simulations of bone remodelling using a bone cell population model based on cell availability
(Frontiers, 2023)
Here we developed a spatio-temporal bone remodeling model to simulate the action of Basic Multicelluar Units (BMUs). This model is based on two major extensions of a temporal-only bone cell population model (BCPM). First, ...
Article
Evolution of relaxation properties of callus tissue during bone transport
(Sage, 2022-09)
Callus tissue exhibits a viscoelastic behavior that has a strong influence on the distribution of stresses and their evolution with time and, thus, it can affect tissue differentiation during distraction procedures. For ...
Article
Mechanistic PK-PD model of alendronate treatment of postmenopausal osteoporosis predicts bone site-specific response
(Frontiers Media S.A., 2022-08-17)
Alendronate is the most widely used drug for postmenopausal osteoporosis (PMO). It inhibits bone resorption, affecting osteoclasts. Pharmacokinetics (PK) and pharmacodynamics (PD) of alendronate have been widely studied, ...
Presentation
Preliminary Study on the Onset of Necking Detection Using DIT in Tensile Tests
(Trans Tech Publications Ltd., 2022-07-22)
The experimental detection of localized necking is an important issue in sheet metal forming. Today, the most common and extended techniques are strain-based methods using digital image correlation (DIC). The present work ...
Presentation
Numerical analysis of flanging using tailored rubber pad forming on AA7075-O sheets
(Material Research Forum LLC, 2024)
The flanging of metal sheets is extensively used in the automotive and aeronautical industries to provide rigidity or support for subsequent assembly. Flanging by rubber pad forming is one of the most common processes for ...
Presentation
Formability analysis of incrementally hole-flanged parts using different tool sizes
(Material Research Forum LLC, 2024)
This contribution analyses the formability of incrementally hole flanged parts using different tool radii (10, 20 and 47.9 mm). The smallest radius (10 mm) can induce full incremental benefits in the hole-flanged specimen, ...