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Article
Solving molecular flexible docking problems with metaheuristics: A comparative study
(Elsevier, 2015)
The main objective of the molecular docking problem is to find a conformation between a small molecule (ligand) and a receptor molecule with minimum binding energy. The quality of the docking score depends on two factors: ...
Article
Intelligent OLSR Routing Protocol Optimization for VANETs
(IEEE Computer Society, 2012)
Recent advances in wireless technologies have given rise to the emergence of vehicular ad hoc networks (VANETs). In such networks, the limited coverage ofWiFi and the high mobility of the nodes generate frequent topology ...
Article
Automatic tuning of communication protocols for vehicular ad hoc networks using metaheuristics
(Elsevier, 2010)
The emerging field of vehicular ad hoc networks (VANETs) deals with a set of communicating vehicles which are able to spontaneously interconnect without any pre-existing infrastructure. In such kind of networks, it is ...
Article
Molecular Docking Optimization in the Context of Multi-Drug Resistant and Sensitive EGFR Mutants
(MDPI, 2016)
The human Epidermal Growth Factor (EGFR) plays an important role in signaling pathways, such as cell proliferation and migration. Mutations like G719S, L858R, T790M, G719S/T790M or T790M/L858R can alter its conformation, ...
Article
jMetalSP: A framework for dynamic multi-objective big data optimization
(Elsevier, 2018)
Multi-objective metaheuristics have become popular techniques for dealing with complex optimization problems composed of a number of conflicting functions. Nowadays, we are in the Big Data era, so metaheuristics must be ...
Article
A Study of Multiobjective Metaheuristics When Solving Parameter Scalable Problems
(IEEE Computer Society, 2010)
To evaluate the search capabilities of a multiobjective algorithm, the usual approach is to choose a benchmark of known problems, to perform a fixed number of function evaluations, and to apply a set of quality indicators. ...