Article
Persulfidation is the mechanism underlying sulfide-signaling of autophagy
Author/s | Gotor Martínez, Cecilia
Aroca Aguilar, Ángeles ![]() ![]() ![]() ![]() ![]() ![]() ![]() Romero González, Luis Carlos |
Department | Universidad de Sevilla. Departamento de Bioquímica Vegetal y Biología Molecular |
Publication Date | 2021 |
Deposit Date | 2021-06-18 |
Published in |
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Abstract | In this commentary, we highlight the findings described in a recent paper regarding the mechanism of H2S regulation of macroautophagy/autophagy in mammalian cells and discuss the similarities/divergencies with plant cells. ... In this commentary, we highlight the findings described in a recent paper regarding the mechanism of H2S regulation of macroautophagy/autophagy in mammalian cells and discuss the similarities/divergencies with plant cells. The main outcome is that the posttranslational modification of thiol groups of cysteine residues to form persulfides is a conserved molecular mechanism. |
Funding agencies | Agencia Estatal de Investigación. España PID2019- 109785GB-I00 |
Project ID. | PID2019- 109785GB-I00
![]() P18-RT-3154 ![]() US-1255781 ![]() 834120 ![]() |
Citation | Gotor Martínez, C., Aroca Aguilar, Á. y Romero González, L.C. (2021). Persulfidation is the mechanism underlying sulfide-signaling of autophagy. Autophagy |
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