Browsing Artículos (Instituto de Biomedicina de Sevilla (IBIS)) by Title
Now showing items 111-130 of 216
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LAG3 genotype of the donor and clinical outcome after allogeneic transplantation from HLA-identical sibling donors
(Frontiers Media S.A., 2023)Introduction: The association of polymorphisms in molecules involved in the immune response (checkpoint inhibitors) with ...
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Late-onset thymidine kinase 2 deficiency: a review of 18 cases
(Springer Nature, 2019-05-06)BACKGROUND: TK2 gene encodes for mitochondrial thymidine kinase, which phosphorylates the pyrimidine nucleosides thymidine ...
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Liver Fibrosis, Host Genetic and Hepatitis C Virus Related Parameters as Predictive Factors of Response to Therapy against Hepatitis C Virus in HIV/HCV Coinfected Patients
(Public Library of Science, 2014-07-11)Objective: To establish the role of liver fibrosis as a predictive tool of response to pegylated interferon alpha (Peg-IFN) ...
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Liver manifestations in COVID-19 and the influence of pre-existing liver disease in the course of the infection
(Arán Ediciones, S.L., 2021)Introduction: patients with advanced chronic liver disease (CLD) may be at an increased risk of a severe course due ...
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Lupinus angustifolius Protein Hydrolysates Reduce Abdominal Adiposity and Ameliorate Metabolic Associated Fatty Liver Disease (MAFLD) in Western Diet Fed-ApoE−/− Mice
(MDPI, 2021-07-29)Metabolic-associated fatty liver disease (MAFLD) is the most important cause of liver disease worldwide. It is characterized ...
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Machine learning models for the differential diagnosis of vascular parkinsonism and Parkinson's disease using [(123)I]FP-CIT SPECT
(Springer, 2015)Purpose: The study’s objective was to develop diagnostic predictive models using data from two commonly used [(123)I]FP-CIT ...
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Melatonin-synthesizing enzymes and melatonin receptor in rat thyroid cells
(Universidad de Murcia. Departamento de Biología Celular e Histología, 2012-11)Melatonin is an indoleamine with a wide spectrum of biological activities other than transmitting photoperiod information, ...
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Mesenchymal stem cells expanded in vitro with human serum for the treatment of acute and chronic graft-versus-host disease: results of a phase I/II clinical trial
(2011)This trial evaluated the feasibility and efficacy of the infusion of mesenchymal stem cells expanded using human serum ...
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Metabolic characterization of two different non-alcoholic fatty liver disease pre-clinical mouse models
(Aran Ediciones S.A., 2019)Introduction: non-alcoholic fatty liver disease is one of the most prevalent liver disorders in the developed world. ...
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Metallo-Liposomes of Ruthenium Used as Promising Vectors of Genetic Material
(MDPI, 2020)Gene therapy is a therapeutic process consisting of the transport of genetic material into cells. The design and preparation ...
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miR-7 Modulates hESC Differentiation into Insulin-Producing Beta-like Cells and Contributes to Cell Maturation
(The American Society of Gene and Cell Therapy, 2018-09-07)Human pluripotent stem cells retain the extraordinary capacity to differentiate into pancreatic beta cells. For this ...
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Molecular landscape and validation of new genomic classification in 2668 adult AML patients: real life data from the PETHEMA registry
(MDPI, 2023)Next–Generation Sequencing (NGS) implementation to perform accurate diagnosis in acute myeloid leukemia (AML) represents ...
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Multidrug resistance transporter profile reveals MDR3 as a marker for stratification of blastemal Wilms tumour patients
(Impact Journals, 2017)Wilms tumour (WT) is the most common renal tumour in children. Most WT patients respond to chemotherapy, but subsets of ...
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Mutational Spectrum of Semaphorin 3A and Semaphorin 3D Genes in Spanish Hirschsprung patients
(Public Library of Science, 2013-01-23)Hirschsprung disease (HSCR, OMIM 142623) is a developmental disorder characterized by the absence of ganglion cells along ...
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Nanostructured fibrin agarose hydrogel as a novel haemostatic agent
(Wiley, 2019)Blood loss remains a major concern during surgery and can increase the morbidity of the intervention. The use of topical ...
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Nestin(+) cells direct inflammatory cell migration in atherosclerosis
(Nature Research, 2016)Atherosclerosis is a leading death cause. Endothelial and smooth muscle cells participate in atherogenesis, but it is ...
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Neural crest derived progenitor cells contribute to tumor stroma and aggressiveness in stage 4/M neuroblastoma
(Impact Journals, 2017)Pediatric tumors arise upon oncogenic transformation of stem/progenitor cells during embryonic development. Given this ...
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Neurocognitive Function in Acromegaly after Surgical Resection of GH-Secreting Adenoma versus Naïve Acromegaly
(Elsevier, 2013-04-04)Patients with active untreated acromegaly show mild to moderate neurocognitive disorders that are associated to chronic ...