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Mostrando ítems 21-30 de 238
Artículo
Influence of Femtosecond Laser Modification on Biomechanical and Biofunctional Behavior of Porous Titanium Substrates
(MDPI, 2022-04)
Bone resorption and inadequate osseointegration are considered the main problems of titanium implants. In this investigation, the texture and surface roughness of porous titanium samples obtained by the space holder technique ...
Artículo
Síntesis del 2-amino-2-desoxi-d-glicero-d-ido-heptononitrilo y de algunos de sus derivados
(1979)
Treatment of a suspension of !l-0-glucopyranosylamine in pyridine with dry hydro gen cyanide affords, at room temperature. in good yield, 2-amino-2 -deoxy-O·g/ycero·O·ido· heptononitrile (1). The structure of 1 is assigned ...
Tesis Doctoral
Diseño y síntesis de nuevos agentes quimioterápicos: receptores acoplados a proteína G (NK1 y CB2) y factores de transcripción (Nrf2 y STAT3) como dianas terapéuticas
(2022-12-02)
El cáncer es una enfermedad de gran impacto sanitario, económico y social en la población, para la que aún no se dispone de un tratamiento eficaz. Por ello, en la presente tesis doctoral nos hemos propuesto el desarrollo ...
Artículo
Investigation of TNBC in vitro Antiproliferative Effects of Versatile Pirrolo[1,2-a]quinoxaline Compounds
(Frontiers Media, 2019)
he triple-negative breast cancer (TNBC) is characterized by a more aggressive nature and poorer prognosis, nowadays none pharmaceutical approach is still available. For this reason, the research of new active compounds and ...
Artículo
Bi-Magnetic Core-Shell CoFe2O4@MnFe2O4 Nanoparticles for In Vivo Theranostics
(MDPI, 2020)
In this work, we report the synthesis and characterization of three magnetic nanosystems, CoFe2O4, CoFe2O4@ZnFe2O4, and CoFe2O4@MnFe2O4, which were developed as potential theranostic agents for magnetic hyperthermia and ...
Artículo
Solving the Hydration Structure of the Heaviest Actinide Aqua IonKnown: The Californium(III) Case
(Wiley-Blackwell, 2010)
Wish they all could be californium: X-ray absorption spectroscopy (black points) and Monte Carlo simulations (blue line) of Cf" in aqueous solutions have been combined to determine the ligand distance and coordination ...
Artículo
(R)-8-Methylsulfinyloctyl isothiocyanate from Nasturtium officinale inhibits LPS-induced immunoinflammatory responses in mouse peritoneal macrophages: chemical synthesis and molecular signaling pathways involved
(Royal Society of Chemistry, 2023-07-20)
The aim of this study was to develop an optimal synthetic route to obtain natural (R)-8-methylsulfinyloctyl isothiocyanate ((R)-8-OITC), present in watercress, based on the “DAG methodology” as well as to evaluate its ...
Tesis Doctoral
Síntesis de derivados de azufre homoquirales
(1998-06-29)
Artículo
DMAP-Catalysed Sulfinylation of Diacetone-D-Glucose: Improved Method for the Synthesis of Enantiopure tert-Butyl Sulfoxides and tert-Butanesulfinamide
(Wiley Online Library, 2014-11)
An improved method for the tert-butanesulfinylation of diacetone glucose with tert-butanesulfinyl chloride is reported. The method is based on a beneficial effect of catalytic DMAP, which enhances both the rate of the ...
Artículo
Preventive oral treatment with resveratrol pro-prodrugs drastically reduce colon inflammation in rodents
(American Chemical Society, 2010-10-28)
There is no pharmaceutical or definitive surgical cure for inflammatory bowel diseases (IBDs). The naturally occurring polyphenol resveratrol exerts anti-inflammatory properties. However, its rapid metabolism diminishes ...