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Mostrando ítems 11-20 de 23
Artículo
Consensus on the Management of the COPD Patient in the COVID-19 Setting COPD Forum Working Group
(Doyma, 2022-11-01)
Since the beginning of the COVID-19 SARS-CoV-2 pandemic, numerous papers have been published on strategic planning and the positioning of different medical societies in the prevention and management of chronic obstructive ...
Artículo
The Human Mycobiome in Chronic Respiratory Diseases: Current Situation and Future Perspectives
(MDPI, 2022)
Microbes play an important role in the pathogenesis of chronic lung diseases, such as chronic obstructive pulmonary disease, cystic fibrosis, non-cystic fibrosis bronchiectasis, and asthma. While the role of bacterial ...
Artículo
Methodologies for the Determination of Blood Alpha1 Antitrypsin Levels: A Systematic Review
(MDPI, 2021-10-31)
Background: The study of hematic concentrations of alpha1 antitrypsin (AAT) is currently one step in the diagnosis of AAT deficiency. To try to clarify the relevance of the laboratory techniques, we carried out a systematic ...
Artículo
Predictors of single bronchodilation treatment response for copd: an observational study with the trace database cohort
(MDPI, 2021-04-15)
Chronic obstructive pulmonary disease (COPD) patients constitute a heterogeneous population in terms of treatment response. Our objective was to identify possible predictive factors of response to treatment with single ...
Artículo
Feasibility of a genotyping system for the diagnosis of alpha1 antitrypsin defciency: a multinational cross‑sectional analysis
(Biomed Central LTD, 2022)
Introduction: Currently, strategies for improving alpha1 antitrypsin defciency (AATD) diagnosis are needed. Here we report the performance of a multinational multiplex-based genotyping test on dried blood spots and buccal ...
Artículo
COPD Exacerbation Syndrome: The Spanish Perspective on an Old Dilemma
(Taylor and Francis Group, 2022-12-29)
The definition of exacerbation of COPD as a syndrome, as proposed by the Spanish COPD guidelines (GesEPOC) 2021 update, and the consequences that this implies, have direct implications on patient care. This review analyzes ...
Artículo
Research priorities to address the global burden of chronic obstructive pulmonary disease (COPD) in the next decade
(Edinburgh University Global Health Society, 2021)
Background: The global prevalence of chronic obstructive pulmonary disease (COPD) has increased markedly in recent decades. Given the scarcity of resources available to address global health challenges and respiratory ...
Artículo
Implications of a Change of Paradigm in Alpha1 Antitrypsin Deficiency Augmentation Therapy: From Biochemical to Clinical Efficacy
(2020-08-05)
Ever since the first studies, restoring proteinase imbalance in the lung has traditionally been considered as the main goal of alpha1 antitrypsin (AAT) replacement therapy. This strategy was therefore based on ensuring ...
Artículo
Effectiveness of aprepitant in post-acute COVID19 syndrome
(Wiley Open Access, 2021-09-18)
This is the first case of a patient taking aprepitant for a post-acute COVID-19 syndrome. This case may encourage researchers to look for the evidence for the efficacy and safety of a neurokinin 1 receptor antagonist in ...
Artículo
Cellular mechanisms involved in the pathogenesis of airway remodeling in chronic lung disease
(Taylor and Francis LTD, 2022)
Background: Airway epithelial cells and lung fibroblasts play an important role in the develop-ment of chronic lung disease, but the exact mechanisms responsible have not been clarified. Our objective was to investigate ...