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Artículo
Current HHT genetic overview in Spain and its phenotypic correlation: data from RiHHTa registry
(Biomed central LTD, 2020)
Background: Hereditary hemorrhagic telangiectasia (HHT) is a rare vascular disease with autosomal dominant inheritance. Disease-causing variants in endoglin (ENG) and activin A receptor type II-like 1 (ACVRL1) genes are ...
Artículo
The PREDICT study uncovers three clinical courses of acutely decompensated cirrhosis that have distinct pathophysiology
(Elsevier, 2020)
Herein, we describe, for the first time, 3 different clinical courses of acute decompensation (AD) of cirrhosis after hospital admission. The first clinical course includes patients who develop acute-on-chronic liver failure ...
Artículo
Pacing for patients suffering from cardioinhibitory vasovagal syncope using the closed-loop system
(Frontiers Media, 2020)
One in three vasovagal syncope (VVS) patients has syncopal recurrence after diagnosis, despite the standard recommendations for the avoidance of a recurrence, and one in five patients has more than one syncopal recurrence ...
Artículo
Stratification of patients in NASH clinical trials: a pitfall for trial success
(Elsevier, 2020)
Identifying the most effective therapeutic intervention in patients with NAFLD is challenging. Precise stratification in clinical trials is key to ensuring the inclusion of patients who will benefit (and not those who will ...
Artículo
A framework to develop semiautomated surveillance of surgical site infections: An international multicenter study
(Cambridge University Press, 2020)
Objective: Automated surveillance of healthcare-associated infections reduces workload and improves standardization, but it has not yet been adopted widely. In this study, we assessed the performance and feasibility of ...
Artículo
Relationship between resilience and quality of life in patients with fear of hypoglycemia: The mediating effects of anxiety and depression
(MDPI, 2020)
Background: Fear of hypoglycemia is an important problem in individuals with diabetes and could produce a negative impact on blood glucose control and quality of life in individuals with type 1 diabetes. Aim: To analyze ...
Artículo
The European NAFLD Registry: A real-world longitudinal cohort study of nonalcoholic fatty liver disease
(Elsevier, 2020)
Non-Alcoholic Fatty Liver Disease (NAFLD), a progressive liver disease that is closely associated with obesity, type 2 diabetes, hypertension and dyslipidaemia, represents an increasing global public health challenge. There ...
Tesis Doctoral
Comparación de la producción local y sistemática de mediadores inflamatorios en distintos grupos celulares de pacientes con enfermedad pulmonar obstructiva crónica
(2020-06-26)
La enfermedad pulmonar obstructiva crónica (EPOC) es una enfermedad común, prevenible y tratable, que se caracteriza por la presencia de síntomas respiratorios persistentes y una limitación al flujo aéreo que se debe a ...
Artículo
¿Mienten los pacientes con EPOC sobre su hábito tabáquico?
(Elsevier, 2020)
Objetivo: Determinar la tasa de decepción o concordancia entre la respuesta de los pacientes con enfermedad pulmonar obstructiva crónica (EPOC) sobre su hábito tabáquico y la medición del mismo por cooximetría en una ...
Artículo
Optimizing design of research to evaluate antibiotic stewardship interventions: consensus recommendations of a multinational working group
(Elsevier, 2020)
Background Antimicrobial stewardship interventions and programmes aim to ensure effective treatment while minimizing antimicrobial-associated harms including resistance. Practice in this vital area is undermined by the ...