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Clinical Viability of Boron Neutron Capture Therapy for Personalized Radiation Treatment
(MDPI, 2022)
bstract: Boron Neutron Capture Therapy (BNCT) is a promising binary disease-targeted therapy, as neutrons preferentially kill cells labeled with boron (10B), which makes it a precision medicine treatment modality that ...
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Transcriptomic analysis reveals an association of FCGBP with Parkinson’s disease
(Nature Research, 2022-11-12)
Transcriptomics in Parkinson’s disease (PD) offers new insights into the molecular mechanism of PD pathogenesis. Several pathways, such as inflammation and protein degradation, have been identified by differential gene ...
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IGF-1 regulates astrocytic phagocytosis and inflammation through the p110α isoform of PI3K in a sex-specific manner
(Willey, 2022)
Insulin-like growth factor-I (IGF-I) signaling plays a key role in neuroinflammation. Here we show that IGF-1 also regulates phagocytosis of reactive astrocytes through p110α isoform of phosphatidylinositol 3-kinase ...
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Exocytosis of catecholamine (CA)-containing and CA-free granules in chromaffin cells
(Science Direct, 2001-08-27)
Recent evidence suggests that endocytosis in neuroendocrine cells and neurons can be tightly coupled to exocytosis, allowing rapid retrieval from the plasma membrane of fused vesicles for future use. This can be a much ...