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Artículo
Critical Requirement of SOS1 for Development of BCR/ABL-Driven Chronic Myelogenous Leukemia
(MDPI, 2022-08-11)
We showed previously that the ABL-mediated phosphorylation of SOS1 promotes RAC activation and contributes to BCR-ABL leukemogenesis, suggesting the relevant role of SOS1 in the pathogenesis of CML. To try and obtain direct ...