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Mostrando ítems 1-10 de 26
Artículo
Transcriptomic and connectomic correlates of differential spatial patterning among gliomas
(Oxford University Press, 2022-10-18)
Unravelling the complex events driving grade-specific spatial distribution of brain tumour occurrence requires rich datasets from both healthy individuals and patients. Here, we combined open-access data from The Cancer ...
Artículo
Connectivity-based parcellation of normal and anatomically distorted human cerebral cortex
(WILEY, 2022)
For over a century, neuroscientists have been working toward parcellating the human cortex into distinct neurobiological regions. Modern technologies offer many parcellation methods for healthy cortices acquired through ...
Artículo
Brain charts for the human lifespan
(Nature Publishing Group, 2022)
Over the past few decades, neuroimaging has become a ubiquitous tool in basic research and clinical studies of the human brain. However, no reference standards currently exist to quantify individual diferences in ...
Artículo
Compulsivity is linked to reduced adolescentdevelopment of goal-directed control andfrontostriatal functional connectivity
(National Academy of Sciences, 2020)
A characteristic of adaptive behavior is its goal-directed nature. Anability to act in a goal-directed manner is progressively refinedduring development, but this refinement can be impacted by theemergence of psychiatric ...
Artículo
Transcriptomic and cellular decoding of regional brain vulnerability to neurogenetic disorders
(Nature Portfolio, 2020)
Neurodevelopmental disorders have a heritable component and are associated with region specific alterations in brain anatomy. However, it is unclear how genetic risks for neurodevelopmental disorders are translated into ...
Artículo
Atypical measures of diffusion at the gray-white matter boundary in autism spectrum disorder in adulthood
(Wiley Open Access, 2020-10-23)
Autism spectrum disorder (ASD) is a highly complex neurodevelopmental condition that is accompanied by neuroanatomical differences on the macroscopic and microscopic level. Findings from histological, genetic, and more ...
Artículo
Lesion covariance networks reveal proposed origins and pathways of diffuse gliomas
(Oxford University Press, 2021-12-04)
Diffuse gliomas have been hypothesized to originate from neural stem cells in the subventricular zone and develop along previously healthy brain networks. Here, we evaluated these hypotheses by mapping independent sources ...
Artículo
Interventional neurorehabilitation for promoting functional recovery post-craniotomy: a proof-of-concept
(Nature Publishing Group, 2022)
The human brain is a highly plastic ‘complex’ network—it is highly resilient to damage and capable of self-reorganisation after a large perturbation. Clinically, neurological deficits secondary to iatrogenic injury have ...
Artículo
Genetic, cellular, and connectomic characterization of the brain regions commonly plagued by glioma
(Oxford University Press, 2020)
For decades, it has been known that gliomas follow a non-random spatial distribution, appearing more often in some brain regions (e.g. the insula) compared to others (e.g. the occipital lobe). A better understanding of the ...
Artículo
A deep graph neural network architecture for modelling spatio-temporal dynamics in resting-state functional MRI data
(Elsevier Science B.V, 2022)
Resting-state functional magnetic resonance imaging (rs-fMRI) has been successfully employed to understand the organisation of the human brain. Typically, the brain is parcellated into regions of interest (ROIs) and modelled ...